Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The protein with two faces - characterization of a dual-activity deoxyhupusine synthase from Trichomonas vaginalis

2019/35/N/NZ1/02805

Keywords:

hypusination trichomonas vaginalis structural biology macromolecular crystallography

Descriptors:

  • NZ1_4: Structural biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

Elżbieta Dorota Wątor 

Number of co-investigators in the project: 2

Call: PRELUDIUM 18 - announced on 2019-09-16

Amount awarded: 209 412 PLN

Project start date (Y-m-d): 2020-06-25

Project end date (Y-m-d): 2024-09-24

Project duration:: 51 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders
    Authors:
    Wątor E, Wilk P, Biela A, Rawski M, Zak KM, Steinchen W, Bange G, Glatt S, Grudnik P.
    Academic press:
    Nature Communications (rok: 2023, tom: 14(1), strony: 1698), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-023-37305-2/ - link to the publication