Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Studies on the use of Lab-on-a-chip systems to analyze the regeneration of heart cells.

2019/34/E/ST5/00381

Keywords:

Lab-on-a-chip microsystem nanofibers hypoxia heart regeneration stem cells

Descriptors:

  • ST5_9: Biomaterials, biocompatible materials
  • ST5_5: Polymer materials
  • ST4_7: Electrochemistry, microfluidics in chemistry, sensors

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Warszawska, Wydział Chemiczny

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Elżbieta Jastrzębska 

Number of co-investigators in the project: 7

Call: SONATA BIS 9 - announced on 2019-06-17

Amount awarded: 1 693 480 PLN

Project start date (Y-m-d): 2020-03-31

Project end date (Y-m-d): 2024-11-29

Project duration:: 56 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (12)
  1. Simulation of hypoxia of myocardial cells in microfluidic systems
    Authors:
    A. Kobuszewska, K. Żukowski, E. Jastrzębska, Z. Brzózka
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 15524), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-72660-w - link to the publication
  2. Cardiac tissue modeling using flow microsystems and nanofiber mats: Evaluating hypoxia-induced cellular and molecular changes
    Authors:
    Dominik Kołodziejek, Urszula Sierańska, Zuzanna Iwoń, Iwona Łopianiak, Ewelina Krogulec, Michał Wojasiński, Elżbieta Jastrzębska
    Academic press:
    Sensors and Actuators B – Chemical (rok: 2024, tom: 403, strony: 135169_1-135169_11), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2023.135169 - link to the publication
  3. Study of Stem Cells Influence on Cardiac Cells Cultured with a Cyanide-P-Trifluoromethoxyphenylhydrazone in Organ-on-a-Chip System
    Authors:
    A. Kobuszewska, D. Kolodziejek, M. Wojasinski, T. Ciach, Z. Brzozka, E. Jastrzebska
    Academic press:
    Biosensors (rok: 2021, tom: 11, strony: 131), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/bios11050131 - link to the publication
  4. Simulation of hypoxia of myocardial cells in microfluidic systems
    Authors:
    A. Kobuszewska, K. Żukowski, E. Jastrzębska, Z. Brzózka
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 15524), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-72660-w - link to the publication
  5. Simulation of hypoxia of myocardial cells in microfluidic systems
    Authors:
    A. Kobuszewska, K. Żukowski, E. Jastrzębska, Z. Brzózka
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 15524), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-72660-w - link to the publication
  6. Lab-on-a-chip system integrated with nanofiber mats used as a potential tool to study cardiovascular diseases (CVDs)
    Authors:
    A. Kobuszewska, D. Kolodziejek, M. Wojasinski, E. Jastrzebska. T. Ciach, Z. Brzozka
    Academic press:
    Sensors and Actuators B: Chemical (rok: 2021, tom: 330, strony: 129291), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2020.129291 - link to the publication
  7. Magnetic polyurethane nanomaterials: A novel approach for in vitro cardiac cell maturation and culture
    Authors:
    Dominik Kołodziejek, Iwona Łopianiak, Oliwia Tadko, Marcin Drozd, Michał Wojasiński, Elżbieta Jastrzębska
    Academic press:
    Polymer Testing (rok: 2023, tom: 127, strony: 108190 1-9), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.polymertesting.2023.108190 - link to the publication
  8. Improving rodents and humans cardiac cell maturity in vitro through polycaprolactone and polyurethane nanofibers
    Authors:
    Zuzanna Iwon, Ewelina Krogulec, Aleksandra Kierlanczyk, Patrycja Baranowska, Iwona Lopianiak, Michał Wojasinki, Elżbieta Jastrzebska
    Academic press:
    Biomedical Materials (rok: 2024, tom: 19(2), strony: 25031), Wydawca: IOP Science
    Status:
    Published
    DOI:
    10.1088/1748-605X/ad240a - link to the publication
  9. Study of Stem Cells Influence on Cardiac Cells Cultured with a Cyanide-P-Trifluoromethoxyphenylhydrazone in Organ-on-a-Chip System
    Authors:
    A. Kobuszewska, D. Kolodziejek, M. Wojasinski, T. Ciach, Z. Brzozka, E. Jastrzebska
    Academic press:
    Biosensors (rok: 2021, tom: 11, strony: 131), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/bios11050131 - link to the publication
  10. Lab-on-a-chip system integrated with nanofiber mats used as a potential tool to study cardiovascular diseases (CVDs)
    Authors:
    A. Kobuszewska, D. Kolodziejek, M. Wojasinski, E. Jastrzebska. T. Ciach, Z. Brzozka
    Academic press:
    Sensors and Actuators B: Chemical (rok: 2021, tom: 330, strony: 129291), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2020.129291 - link to the publication
  11. Lab-on-a-chip system integrated with nanofiber mats used as a potential tool to study cardiovascular diseases (CVDs)
    Authors:
    A. Kobuszewska, D. Kolodziejek, M. Wojasinski, E. Jastrzebska. T. Ciach, Z. Brzozka
    Academic press:
    Sensors and Actuators B: Chemical (rok: 2021, tom: 330, strony: 129291), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2020.129291 - link to the publication
  12. Study of Stem Cells Influence on Cardiac Cells Cultured with a Cyanide-P-Trifluoromethoxyphenylhydrazone in Organ-on-a-Chip System
    Authors:
    A. Kobuszewska, D. Kolodziejek, M. Wojasinski, T. Ciach, Z. Brzozka, E. Jastrzebska
    Academic press:
    Biosensors (rok: 2021, tom: 11, strony: 131), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/bios11050131 - link to the publication

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