Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Maternal obesity and epigenetic and metabolic regulations during gametogenesis and early embryo development in mice: the specific role of leptin signalling

2019/34/E/NZ4/00349

Keywords:

Obesity Ovary Oocyte Embryo Leptin Methylome Lipidome

Descriptors:

  • NZ2_002:
  • NZ4_011:
  • NZ4_006:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności PAN

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Antonio Miguel Galvao 

Number of co-investigators in the project: 6

Call: SONATA BIS 9 - announced on 2019-06-17

Amount awarded: 3 879 750 PLN

Project start date (Y-m-d): 2020-12-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 58 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Leptin Signaling in the Ovary of Diet-Induced Obese Mice Regulates Activation of NOD-Like Receptor Protein 3 Inflammasome
    Authors:
    Marek Adamowski, Karolina Wołodko, Joana Oliveira, Juan Castillo-Fernandez, Daniel Murta, Gavin Kelsey and António M. Galvão
    Academic press:
    Frontiers in Cell and Developmental Biology , Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fcell.2021.738731 - link to the publication
  2. Revisiting the Impact of Local Leptin Signaling in Folliculogenesis and Oocyte Maturation in Obese Mothers
    Authors:
    Karolina Wołodko, Juan Castillo-Fernandez, Gavin Kelsey and António Galvão
    Academic press:
    International Journal of Molecular Sciences , Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22084270 - link to the publication
  3. Maternal Obesity and Ovarian Failure: is Leptin the Culprit?
    Authors:
    Sharma Yashaswi; Galvão Antonio
    Academic press:
    Animal Reproduction (), Wydawca: Colégio Brasileiro de Reprodução Animal
    Status:
    Published
    DOI:
    10.1590/1984-3143-AR2023-0007 - link to the publication