Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Connecting Artificial Protein Cages

2019/34/A/NZ1/00196

Keywords:

structural biology protein engineering protein design protein cages bionanoscience

Descriptors:

  • NZ1_004:
  • NZ1_001:
  • NZ1_009:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jonathan Gardiner Heddle 

Number of co-investigators in the project: 7

Call: MAESTRO 11 - announced on 2019-06-17

Amount awarded: 4 306 700 PLN

Project start date (Y-m-d): 2020-07-01

Project end date (Y-m-d): 2025-09-30

Project duration:: 63 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (2)
  1. Shape-Morphing of an Artificial Protein Cage with Unusual Geometry Induced by a Single Amino Acid Change
    Authors:
    Mohit Sharma, Artur P. Biela, Agnieszka Kowalczyk, Kinga Borzęcka-Solarz, Bernard M. A. G. Piette, Szymon Gaweł, Joshua Bishop, Philipp Kukura, Justin L. P. Benesch, Motonori Imamura, Simon Scheuring, Jonathan G. Heddle
    Academic press:
    ACS Nanoscience Au (), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsnanoscienceau.2c00019 - link to the publication
  2. An artificial protein cage made from a 12-membered ring
    Authors:
    Stupka, I., Biela, A.P., Piette, B., Kowalczyk, A., Majsterkiewicz, K., Borzęcka-Solarz, K., Naskalska, A. and Heddle, J.G.
    Academic press:
    Journal of Materials Chemistry B (), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/D3TB01659E - link to the publication
  3. Artificial Protein Cage with Unusual Geometry and Regularly Embedded Gold Nanoparticles
    Authors:
    Karolina Majsterkiewicz, Artur P. Biela, Sourav Maity, Mohit Sharma, Bernard M. A. G. Piette, Agnieszka Kowalczyk, Szymon Gaweł, Soumyananda Chakraborti, Wouter H. Roos, Jonathan G. Heddle
    Academic press:
    Nano Letters (tom: 22 (8), strony: 3187-3195), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.nanolett.1c04222 - link to the publication
  4. Programmable polymorphism of a virus-like particle
    Authors:
    Artur P. Biela, Antonina Naskalska, Farzad Fatehi, Reidun Twarock, Jonathan G. Heddle
    Academic press:
    Communications Materials (), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s43246-022-00229-3 - link to the publication
  5. Chemically induced protein cage assembly with programmable opening and cargo release
    Authors:
    Izabela Stupka, Yusuke Azuma, Artur P. Biela, Motonori Imamura, Simon Scheuring, Elżbieta Pyza, Olga Woźnicka, Daniel P. Maskell, Jonathan G. Heddle
    Academic press:
    Science Advances (), Wydawca: American Association for the Advancement of Science
    Status:
    Published
    DOI:
    10.1126/sciadv.abj9424 - link to the publication
  1. Artificial Protein Cages Assembled via Gold Coordination
    Authors:
    Majsterkiewicz, K., Stupka, I., Borzęcka-Solarz, K., Biela, A., Gaweł, S., Pasternak, M., & Heddle, J.
    Book:
    Protein Cages: Design, Structure, and Applications (), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/978-1-0716-3222-2_2 - link to the publication
  2. Running rings around protein cages: a case study of artificial TRAP cages
    Authors:
    Szymon Gaweł ; Antonina Naskalska ; Norbert Osiński ; Jonathan Gardiner Heddle
    Book:
    Amino Acids, Peptides and Proteins (), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/BK9781839169328-00045 - link to the publication