Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Connecting Artificial Protein Cages

2019/34/A/NZ1/00196

Keywords:

structural biology protein engineering protein design protein cages bionanoscience

Descriptors:

  • NZ1_4: Structural biology
  • NZ1_1: Molecular biology
  • NZ1_9: Biotechnology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Jonathan Gardiner Heddle 

Number of co-investigators in the project: 7

Call: MAESTRO 11 - announced on 2019-06-17

Amount awarded: 4 306 700 PLN

Project start date (Y-m-d): 2020-07-01

Project end date (Y-m-d): 2024-06-30

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (12)
  • Book publications / chapters in book publications (2)
  1. Chemically induced protein cage assembly with programmable opening and cargo release
    Authors:
    Izabela Stupka, Yusuke Azuma, Artur P. Biela, Motonori Imamura, Simon Scheuring, Elżbieta Pyza, Olga Woźnicka, Daniel P. Maskell, Jonathan G. Heddle
    Academic press:
    Science Advances (rok: 2022, tom: 8, strony: eabj9424), Wydawca: American Association for the Advancement of Science
    Status:
    Published
    DOI:
    10.1126/sciadv.abj9424 - link to the publication
  2. Programmable polymorphism of a virus-like particle
    Authors:
    Artur P. Biela, Antonina Naskalska, Farzad Fatehi, Reidun Twarock, Jonathan G. Heddle
    Academic press:
    Communications Materials (rok: 2022, tom: 3, strony: Article number: 7 (2022)), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s43246-022-00229-3 - link to the publication
  3. Shape-Morphing of an Artificial Protein Cage with Unusual Geometry Induced by a Single Amino Acid Change
    Authors:
    Mohit Sharma, Artur P. Biela, Agnieszka Kowalczyk, Kinga Borzęcka-Solarz, Bernard M. A. G. Piette, Szymon Gaweł, Joshua Bishop, Philipp Kukura, Justin L. P. Benesch, Motonori Imamura, Simon Scheuring, Jonathan G. Heddle
    Academic press:
    ACS Nanoscience Au (rok: 2022, tom: 2, strony: 404-413), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsnanoscienceau.2c00019 - link to the publication
  4. An artificial protein cage made from a 12-membered ring
    Authors:
    Stupka, I., Biela, A.P., Piette, B., Kowalczyk, A., Majsterkiewicz, K., Borzęcka-Solarz, K., Naskalska, A. and Heddle, J.G.
    Academic press:
    Journal of Materials Chemistry B (rok: 2023, tom: 12, strony: 436-447), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/D3TB01659E - link to the publication
  5. Programmable polymorphism of a virus-like particle
    Authors:
    Artur P. Biela, Antonina Naskalska, Farzad Fatehi, Reidun Twarock, Jonathan G. Heddle
    Academic press:
    Communications Materials (rok: 2022, tom: 3, strony: Article number: 7 (2022)), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s43246-022-00229-3 - link to the publication
  6. Artificial Protein Cage with Unusual Geometry and Regularly Embedded Gold Nanoparticles
    Authors:
    Karolina Majsterkiewicz, Artur P. Biela, Sourav Maity, Mohit Sharma, Bernard M. A. G. Piette, Agnieszka Kowalczyk, Szymon Gaweł, Soumyananda Chakraborti, Wouter H. Roos, Jonathan G. Heddle
    Academic press:
    Nano Letters (rok: 2022, tom: 22 (8), strony: 3187-3195), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.nanolett.1c04222 - link to the publication
  7. Artificial Protein Cage with Unusual Geometry and Regularly Embedded Gold Nanoparticles
    Authors:
    Karolina Majsterkiewicz, Artur P. Biela, Sourav Maity, Mohit Sharma, Bernard M. A. G. Piette, Agnieszka Kowalczyk, Szymon Gaweł, Soumyananda Chakraborti, Wouter H. Roos, Jonathan G. Heddle
    Academic press:
    Nano Letters (rok: 2022, tom: 22 (8), strony: 3187-3195), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.nanolett.1c04222 - link to the publication
  8. Shape-Morphing of an Artificial Protein Cage with Unusual Geometry Induced by a Single Amino Acid Change
    Authors:
    Mohit Sharma, Artur P. Biela, Agnieszka Kowalczyk, Kinga Borzęcka-Solarz, Bernard M. A. G. Piette, Szymon Gaweł, Joshua Bishop, Philipp Kukura, Justin L. P. Benesch, Motonori Imamura, Simon Scheuring, Jonathan G. Heddle
    Academic press:
    ACS Nanoscience Au (rok: 2022, tom: 2, strony: 404-413), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsnanoscienceau.2c00019 - link to the publication
  9. Programmable polymorphism of a virus-like particle
    Authors:
    Artur P. Biela, Antonina Naskalska, Farzad Fatehi, Reidun Twarock, Jonathan G. Heddle
    Academic press:
    Communications Materials (rok: 2022, tom: 3, strony: Article number: 7 (2022)), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s43246-022-00229-3 - link to the publication
  10. Artificial Protein Cage with Unusual Geometry and Regularly Embedded Gold Nanoparticles
    Authors:
    Karolina Majsterkiewicz, Artur P. Biela, Sourav Maity, Mohit Sharma, Bernard M. A. G. Piette, Agnieszka Kowalczyk, Szymon Gaweł, Soumyananda Chakraborti, Wouter H. Roos, Jonathan G. Heddle
    Academic press:
    Nano Letters (rok: 2022, tom: -, strony: -), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.nanolett.1c04222 - link to the publication
  11. Chemically induced protein cage assembly with programmable opening and cargo release
    Authors:
    Izabela Stupka, Yusuke Azuma, Artur P. Biela, Motonori Imamura, Simon Scheuring, Elżbieta Pyza, Olga Woźnicka, Daniel P. Maskell, Jonathan G. Heddle
    Academic press:
    Science Advances (rok: 2022, tom: 8, strony: eabj9424), Wydawca: American Association for the Advancement of Science
    Status:
    Published
    DOI:
    10.1126/sciadv.abj9424 - link to the publication
  12. Chemically induced protein cage assembly with programmable opening and cargo release
    Authors:
    Izabela Stupka, Yusuke Azuma, Artur P. Biela, Motonori Imamura, Simon Scheuring, Elżbieta Pyza, Olga Woźnicka, Daniel P. Maskell, Jonathan G. Heddle
    Academic press:
    Science Advances (rok: 2022, tom: 8, strony: eabj9424), Wydawca: American Association for the Advancement of Science
    Status:
    Published
    DOI:
    10.1126/sciadv.abj9424 - link to the publication
  1. Artificial Protein Cages Assembled via Gold Coordination
    Authors:
    Majsterkiewicz, K., Stupka, I., Borzęcka-Solarz, K., Biela, A., Gaweł, S., Pasternak, M., & Heddle, J.
    Book:
    Protein Cages: Design, Structure, and Applications (rok: 2023, tom: 2671, strony: 49-68), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/978-1-0716-3222-2_2 - link to the publication
  2. Running rings around protein cages: a case study of artificial TRAP cages
    Authors:
    Szymon Gaweł ; Antonina Naskalska ; Norbert Osiński ; Jonathan Gardiner Heddle
    Book:
    Amino Acids, Peptides and Proteins (rok: 2024, tom: 45, strony: 45-63), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/BK9781839169328-00045 - link to the publication

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