Development of a new approach based on microfluidic Lab-on-a-Chip system and pancreatic islets' 3D models to perform high-throughput studies aimed at functional analyses of pancreatic islets under physiological and pathological conditions.
2019/33/N/ST4/02416
Keywords
Descriptors
- ST4_007: Elektrochemia, mikroprzepływy w chemii, sensory
- ST4_009: Chemia biologiczna
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Politechnika Warszawska
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 17 – announced on 2019-03-15
- Amount awarded
- 204 100 PLN
- Project start date
- 2020-02-24
- Project end date
- 2023-02-23
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (4)
-
Islet-on-a-chip: Biomimetic micropillar-based microfluidic system for three-dimensional pancreatic islet cell culture
- Authors:
- Patrycja Sokolowska, Kamil Zukowski, Justyna Janikiewicz, Elzbieta Jastrzebska, Agnieszka Dobrzyn, Zbigniew Brzozka
- Academic press:
- Biosensors and Bioelectronics (year: 2021, volume: 183, pages: 113215), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.bios.2021.113215 – link to the publication
-
Combinations of regenerative medicine and Lab-on-a-chip systems: New hope to restoring the proper function of pancreatic islets in diabetes
- Authors:
- Patrycja Sokolowska, Justyna Janikiewicz, Elzbieta Jastrzebska, Zbigniew Brzozka, Agnieszka Dobrzyn
- Academic press:
- Biosensors and Bioelectronics (year: 2020, volume: 167, pages: 112451), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.bios.2020.112451 – link to the publication
-
Investigation of the Therapeutic Potential of New Antidiabetic Compounds Using Islet-on-a-Chip Microfluidic Model
- Authors:
- Patrycja Sokolowska, Elzbieta Jastrzebska, Agnieszka Dobrzyn, Zbigniew Brzozka
- Academic press:
- Biosensors (year: 2022, volume: 12, pages: 302), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/bios12050302 – link to the publication
-
Why Can Organoids Improve Current Organ-on-Chip Platforms?
- Authors:
- Patrycja Sokolowska, Agnieszka Zuchowska, Zbigniew Brzozka
- Academic press:
- Organoids (year: 2022, volume: 1, pages: 69–84), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/organoids1010007 – link to the publication
Articles in post-conference publications (2)
-
5-Hexadecanoyloxyoctadecanoic Acid (5-PAHSA) as a Potential Therapeutic Agent in Diabetes? Preliminary Studies Using the Newly Developed, Fully Functional Islet-on-a-Chip Model
- Authors:
- Patrycja Sokołowska, Elzbieta Jastrzebska, Zbigniew Brzózka
- Conference:
- Engineering proceedings (year: 2022, volume: 9th International Symposium on Sensor Science (I3S 2022), pages: 7), Publisher: MDPI
- Date:
- conference 20.06.2022 - 22.06.2022
- Status:
- Published
- DOI:
- 10.3390/engproc2022021007 – link to the publication
-
Micropillar-based microfluidic system for studies of 3D pancreatic islet structures
- Authors:
- Patrycja Sokolowska, Anna Grabowska, Kamil Zukowski, Justyna Janikiewicz, Elzbieta Jastrzebska, Zbigniew Brzozka, Agnieszka Dobrzyn
- Conference:
- 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2020) (year: 2020, volume: The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2020), pages: 987 - 988), Publisher: Chemical and Biological Microsystems Society (CBMS)
- Date:
- conference 4-9.10.2020
- Status:
- Published