Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Cancer-Omics. Vibrational Imaging and Endospectroscopy Takes Cancer Research to the Next Level

2019/33/B/ST4/01961

Keywords:

Raman imaging cancer research AFM oncological diagnostics epigenetic modifications in cancer lipid phenotype

Descriptors:

  • ST4_2: Spectroscopic and spectrometric techniques
  • NZ1_3: Biophysics
  • NZ4_11: Metabolism

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Łódzka, Wydział Chemiczny

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Halina Abramczyk 

Number of co-investigators in the project: 9

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 1 200 900 PLN

Project start date (Y-m-d): 2020-01-30

Project end date (Y-m-d): 2024-01-29

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (24)
  1. Nitrogen-Doped Titanium Dioxide Nanoparticles Modified by an Electron Beam for Improving Human Breast Cancer Detection by Raman Spectroscopy: A Preliminary Study
    Authors:
    Jakub Surmacki
    Academic press:
    Diagnostics (rok: 2020, tom: 10, strony: 45667), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/diagnostics10100757 - link to the publication
  2. Confocal Raman imaging reveals the impact of retinoids on human breast cancer via monitoring the redox status of cytochrome c
    Authors:
    Jakub Maciej Surmacki, Halina Abramczyk
    Academic press:
    Scientific Reports (rok: 2023, tom: 13(1), strony: 45668), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-42301-z - link to the publication
  3. Raman imaging and statistical methods for analysis various type of human brain tumors and breast cancers
    Authors:
    Monika Kopec, Maciej Blaszczyk, Maciej Radek, Halina Abramczyk
    Academic press:
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (rok: 2021, tom: 262, strony: 45668), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.saa.2021.120091 - link to the publication
  4. Revision of Commonly Accepted Warburg Mechanism of Cancer Development: Redox-Sensitive Mitochondrial Cytochromes in Breast and Brain Cancers by Raman Imaging
    Authors:
    Halina Abramczyk, Jakub Maciej Surmacki, Beata Brozek-Pluska, Monika Kopec
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 45680), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13112599 - link to the publication
  5. Raman imaging and statistical methods for analysis various type of human brain tumors and breast cancers
    Authors:
    Monika Kopec, Maciej Blaszczyk, Maciej Radek, Halina Abramczyk
    Academic press:
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (rok: 2021, tom: 262, strony: 45668), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.saa.2021.120091 - link to the publication
  6. Novel strategies of Raman imaging for monitoring intracellular retinoid metabolism in cancer cells
    Authors:
    Halina Abramczyk, Anna Imiela, Jakub Surmacki
    Academic press:
    Journal of Molecular Liquids (rok: 2021, tom: 334, strony: 45673), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molliq.2021.116033 - link to the publication
  7. Redox Imbalance and Biochemical Changes in Cancer by Probing Redox-Sensitive Mitochondrial Cytochromes in Label-Free Visible Resonance Raman Imaging
    Authors:
    Halina Abramczyk, Beata Brozek-Pluska, Monika Kopec, Jakub Surmacki, Maciej Blaszczyk, Maciej Radek
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 45677), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13050960 - link to the publication
  8. The role of pro- and antiangiogenic factors in angiogenesis process by Raman spectroscopy
    Authors:
    Monika Kopec, Halina Abramczyk
    Academic press:
    Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy (rok: 2022, tom: 268, strony: 45667), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.saa.2021.120667 - link to the publication
  9. Double face of cytochrome c in cancers by Raman imaging
    Authors:
    Halina Abramczyk, Beata Brozek-Pluska, Monika Kopec
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 45668), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-04803-0 - link to the publication
  10. Redox state changes of mitochondrial cytochromes in brain and breast cancers by Raman spectroscopy and imaging
    Authors:
    Halina Abramczyk, Jakub Maciej Surmacki, Beata Brozek-Pluska
    Academic press:
    Journal of Molecular Structure (rok: 2022, tom: 1252, strony: 45669), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2021.132134 - link to the publication
  11. Novel strategies of Raman imaging for monitoring intracellular retinoid metabolism in cancer cells
    Authors:
    Halina Abramczyk, Anna Imiela, Jakub Surmacki
    Academic press:
    Journal of Molecular Liquids (rok: 2021, tom: 334, strony: 45673), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molliq.2021.116033 - link to the publication
  12. Double face of cytochrome c in cancers by Raman imaging
    Authors:
    Halina Abramczyk, Beata Brozek-Pluska, Monika Kopec
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 45668), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-04803-0 - link to the publication
  13. Redox Imbalance and Biochemical Changes in Cancer by Probing Redox-Sensitive Mitochondrial Cytochromes in Label-Free Visible Resonance Raman Imaging
    Authors:
    Halina Abramczyk, Beata Brozek-Pluska, Monika Kopec, Jakub Surmacki, Maciej Blaszczyk, Maciej Radek
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 45677), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13050960 - link to the publication
  14. Revision of Commonly Accepted Warburg Mechanism of Cancer Development: Redox-Sensitive Mitochondrial Cytochromes in Breast and Brain Cancers by Raman Imaging
    Authors:
    Halina Abramczyk, Jakub Maciej Surmacki, Beata Brozek-Pluska, Monika Kopec
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 45680), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13112599 - link to the publication
  15. Revision of Commonly Accepted Warburg Mechanism of Cancer Development: Redox-Sensitive Mitochondrial Cytochromes in Breast and Brain Cancers by Raman Imaging
    Authors:
    Halina Abramczyk, Jakub Maciej Surmacki, Beata Brozek-Pluska, Monika Kopec
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 45680), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13112599 - link to the publication
  16. Raman imaging and statistical methods for analysis various type of human brain tumors and breast cancers
    Authors:
    Monika Kopec, Maciej Blaszczyk, Maciej Radek, Halina Abramczyk
    Academic press:
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (rok: 2021, tom: 262, strony: 45668), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.saa.2021.120091 - link to the publication
  17. Novel strategies of Raman imaging for monitoring intracellular retinoid metabolism in cancer cells
    Authors:
    Halina Abramczyk, Anna Imiela, Jakub Surmacki
    Academic press:
    Journal of Molecular Liquids (rok: 2021, tom: 334, strony: 45673), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molliq.2021.116033 - link to the publication
  18. Decoding Breast Cancer Metabolism: Hunting BRCA Mutations by Raman Spectroscopy
    Authors:
    Monika Kopec, Beata Romanowska-Pietrasiak, Halina Abramczyk
    Academic press:
    photochem (rok: 2022, tom: 2, strony: 752-764), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/photochem2030048 - link to the publication
  19. Redox state changes of mitochondrial cytochromes in brain and breast cancers by Raman spectroscopy and imaging
    Authors:
    Halina Abramczyk, Jakub Maciej Surmacki, Beata Brozek-Pluska
    Academic press:
    Journal of Molecular Structure (rok: 2022, tom: 1252, strony: 45669), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2021.132134 - link to the publication
  20. Nitrogen-Doped Titanium Dioxide Nanoparticles Modified by an Electron Beam for Improving Human Breast Cancer Detection by Raman Spectroscopy: A Preliminary Study
    Authors:
    Jakub Surmacki
    Academic press:
    Diagnostics (rok: 2020, tom: 10, strony: 45667), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/diagnostics10100757 - link to the publication
  21. The role of pro- and antiangiogenic factors in angiogenesis process by Raman spectroscopy
    Authors:
    Monika Kopec, Halina Abramczyk
    Academic press:
    Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy (rok: 2022, tom: 268, strony: 45667), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.saa.2021.120667 - link to the publication
  22. Decoding Breast Cancer Metabolism: Hunting BRCA Mutations by Raman Spectroscopy
    Authors:
    Monika Kopec, Beata Romanowska-Pietrasiak, Halina Abramczyk
    Academic press:
    photochem (rok: 2022, tom: 2, strony: 752-764), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/photochem2030048 - link to the publication
  23. Redox Imbalance and Biochemical Changes in Cancer by Probing Redox-Sensitive Mitochondrial Cytochromes in Label-Free Visible Resonance Raman Imaging
    Authors:
    Halina Abramczyk, Beata Brozek-Pluska, Monika Kopec, Jakub Surmacki, Maciej Blaszczyk, Maciej Radek
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 45677), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13050960 - link to the publication
  24. Nitrogen-Doped Titanium Dioxide Nanoparticles Modified by an Electron Beam for Improving Human Breast Cancer Detection by Raman Spectroscopy: A Preliminary Study
    Authors:
    Jakub Surmacki
    Academic press:
    Diagnostics (rok: 2020, tom: 10, strony: 45667), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/diagnostics10100757 - link to the publication

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