Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The immune checkpoints in non-small cell lung cancer - research on genetic and epigenetic mechanism regulating mRNA and protein expression

2019/33/B/NZ5/03029

Keywords:

immune checkpoints PD1 BTLA LAG-3 TIGIT TIM3 non-small cell lung cancer epigenetics methylation miRNA mRNA expression protein expression

Descriptors:

  • NZ2_6: Immunogenetics
  • NZ5_3: Pathogenesis of human diseases
  • NZ6_2: Clinical immunology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Monika Jasek 

Number of co-investigators in the project: 14

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 2 257 528 PLN

Project start date (Y-m-d): 2020-02-27

Project end date (Y-m-d): 2025-02-26

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. The association of BTLA gene polymorphisms with non-small lung cancer risk in smokers and never-smokers
    Authors:
    Anna Andrzejczak, Anna Partyka, Andrzej Wiśniewski, Irena Porębska, Konrad Pawełczyk, Kuba Ptaszkowski, Piotr Kuśnierczyk, Monika Jasek, Lidia Karabon
    Academic press:
    Frontiers in Immunology (rok: 2023, tom: 13, strony: 20), Wydawca: frontiers.org
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.1006639 - link to the publication
  2. Common inherited variants of PDCD1, CD274 and HAVCR2 genes differentially modulate the risk and prognosis of adenocarcinoma and squamous cell carcinoma
    Authors:
    Nafeesa Moksud, Marta Wagner, Konrad Pawełczyk, Irena Porębska, Beata Muszczyńska-Bernhard, Aneta Kowal, Andrzej Wiśniewski, Monika Kosacka , Julia Kończak, Paweł Karpiński, Dominik Frydryk, Anna Andrzejczak, Lidia Karabon, Piotr Kuśnierczyk, Monika Jasek
    Academic press:
    Journal of Cancer Research and Clinical Oncology (rok: 2023, tom: bd, strony: bd), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00432-023-04602-8 - link to the publication
  3. Immune Checkpoint Molecules-Inherited Variations as Markers for Cancer Risk
    Authors:
    Marta Wagner, Monika Jasek, Lidia Karabon
    Academic press:
    Frontiers in Immunology (rok: 2021, )
    Status:
    Published
    DOI:
    link to the publication
  4. The association of BTLA gene polymorphisms with non-small lung cancer risk in smokers and never-smokers
    Authors:
    Anna Andrzejczak, Anna Partyka, Andrzej Wiśniewski, Irena Porębska, Konrad Pawełczyk, Kuba Ptaszkowski, Piotr Kuśnierczyk, Monika Jasek, Lidia Karabon
    Academic press:
    Frontiers in Immunology (rok: 2023, tom: 13, strony: 20), Wydawca: frontiers.org
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.1006639 - link to the publication
  5. Immune Checkpoint Molecules-Inherited Variations as Markers for Cancer Risk
    Authors:
    Marta Wagner, Monika Jasek, Lidia Karabon
    Academic press:
    Frontiers in Immunology (rok: 2021, )
    Status:
    Published
    DOI:
    link to the publication
  6. Common inherited variants of PDCD1, CD274 and HAVCR2 genes differentially modulate the risk and prognosis of adenocarcinoma and squamous cell carcinoma
    Authors:
    Nafeesa Moksud, Marta Wagner, Konrad Pawełczyk, Irena Porębska, Beata Muszczyńska-Bernhard, Aneta Kowal, Andrzej Wiśniewski, Monika Kosacka , Julia Kończak, Paweł Karpiński, Dominik Frydryk, Anna Andrzejczak, Lidia Karabon, Piotr Kuśnierczyk, Monika Jasek
    Academic press:
    Journal of Cancer Research and Clinical Oncology (rok: 2023, tom: bd, strony: bd), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00432-023-04602-8 - link to the publication
  7. Immune Checkpoint Molecules-Inherited Variations as Markers for Cancer Risk
    Authors:
    Marta Wagner, Monika Jasek, Lidia Karabon
    Academic press:
    Frontiers in Immunology (rok: 2021, )
    Status:
    Published
    DOI:
    link to the publication

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