Projects funded by the NCN
The role of lactate and the metabolic GPR81 sensor in the regulation of the function of podocyte and glomerular filtration barrier in normoglycemia and hyperglycemia.
2019/33/B/NZ4/02407
Keywords:
podocyte lactate insulin resistance lactate transporters lypolysis diabetes
Descriptors:
- NZ4_11: Metabolism
- NZ4_4: Pathophysiology
- NZ3_2: Cell physiology
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk
woj.
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 17 - announced on 2019-03-15
Amount awarded: 1 656 195 PLN
Project start date (Y-m-d): 2020-02-06
Project end date (Y-m-d): 2023-11-05
Project duration:: 45 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Insights into the regulation of podocyte and glomerular function by lactate and its metabolic sensor G‐protein‐coupled receptor 81Authors:Klaudia Grochowalska, Piotr Pikul, Agnieszka PiwkowskaAcademic press:Journal of Cellular Physiology (rok: 2022, tom: 237, strony: 4097-4111), Wydawca: WilleyStatus:PublishedDOI:10.1002/jcp.30874 - link to the publication
- Role of L-lactate as an energy substrate in primary rat podocytes under physiological and glucose deprivation conditionsAuthors:Maria Szrejder, Marlena Typiak, Piotr Pikul, Irena Audzeyenka, Patrycja Rachubik, Dorota Rogacka, Magdalena Narajczyk, Agnieszka PiwkowskaAcademic press:European Journal of Cell Biology (rok: 2023, tom: 102, strony: 151298), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.ejcb.2023.151298 - link to the publication