Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Synthesis and biofunctionalization of boron-rich nanoparticles; the application in targeted boron neutron capture therapy

2019/33/B/NZ5/02212

Keywords:

nanparticles functionalization phagocytosis tumor cells biodistribution

Descriptors:

  • NZ5_7: Human disease treatment
  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST5_13: Research methods on materials/nanomaterials properties

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Elżbieta Pajtasz-Piasecka 

Number of co-investigators in the project: 10

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 2 154 800 PLN

Project start date (Y-m-d): 2020-02-18

Project end date (Y-m-d): 2025-02-17

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (11)
  1. Nanocząstki o wysokiej zawartości boru jako potencjalne nośniki w terapii borowo-neutronowej
    Authors:
    Wróblewska A., Szermer-Olearnik B., Pajtasz-Piasecka E.
    Academic press:
    Postepy Hig Med Dosw (rok: 2021, tom: 75, strony: 122-132), Wydawca: Sciendo
    Status:
    Published
    DOI:
    10.5604/01.3001.0014.7760 - link to the publication
  2. Boron-Rich Boron Carbide Nanoparticles as a Carrier in Boron Neutron Capture Therapy: Their Influence on Tumor and Immune Phagocytic Cells
    Authors:
    Dawid Kozień, Bożena Szermer-Olearnik, Andrzej Rapak, Agnieszka Szczygieł, Natalia Anger-Góra, Janusz Boratyński, Elżbieta Pajtasz-Piasecka, Mirosław M. Bućko, Zbigniew Pędzich.
    Academic press:
    Materials (rok: 2021, tom: vol. 14 iss. 11 art. no. 3010, strony: 45670), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14113010 - link to the publication
  3. Nanocząstki o wysokiej zawartości boru jako potencjalne nośniki w terapii borowo-neutronowej
    Authors:
    Wróblewska A., Szermer-Olearnik B., Pajtasz-Piasecka E.
    Academic press:
    Postepy Hig Med Dosw (rok: 2021, tom: 75, strony: 122-132), Wydawca: Sciendo
    Status:
    Published
    DOI:
    10.5604/01.3001.0014.7760 - link to the publication
  4. Macrophages as Promising Carriers for Nanoparticle Delivery in Anticancer Therapy
    Authors:
    Wróblewska A., Szczygieł A., Szermer-Olearnik B., Pajtasz-Piasecka E.
    Academic press:
    International Journal of Nanomedicine (rok: 2023, tom: 84,3041666666667, strony: 4521-4539), Wydawca: Dovepress
    Status:
    Published
    DOI:
    10.2147/IJN.S421173 - link to the publication
  5. Surface Properties and Morphology of Boron Carbide Nanopowders Obtained by Lyophilization of Saccharide Precursors
    Authors:
    Dawid Kozień, Piotr Jeleń, Joanna Stępień, Zbigniew Olejniczak, Maciej Sitarz, Zbigniew Pedzich.
    Academic press:
    Materials (rok: 2021, tom: vol. 14 iss 12 art,. no. 3419, strony: 45673), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14123419 - link to the publication
  6. Boron-Rich Boron Carbide Nanoparticles as a Carrier in Boron Neutron Capture Therapy: Their Influence on Tumor and Immune Phagocytic Cells
    Authors:
    Dawid Kozień, Bożena Szermer-Olearnik, Andrzej Rapak, Agnieszka Szczygieł, Natalia Anger-Góra, Janusz Boratyński, Elżbieta Pajtasz-Piasecka, Mirosław M. Bućko, Zbigniew Pędzich.
    Academic press:
    Materials (rok: 2021, tom: vol. 14 iss. 11 art. no. 3010, strony: 45670), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14113010 - link to the publication
  7. Nanocząstki o wysokiej zawartości boru jako potencjalne nośniki w terapii borowo-neutronowej
    Authors:
    Wróblewska A., Szermer-Olearnik B., Pajtasz-Piasecka E.
    Academic press:
    Postepy Hig Med Dosw (rok: 2021, tom: 75, strony: 122-132), Wydawca: Sciendo
    Status:
    Published
    DOI:
    10.5604/01.3001.0014.7760 - link to the publication
  8. Surface Properties and Morphology of Boron Carbide Nanopowders Obtained by Lyophilization of Saccharide Precursors
    Authors:
    Dawid Kozień, Piotr Jeleń, Joanna Stępień, Zbigniew Olejniczak, Maciej Sitarz, Zbigniew Pedzich.
    Academic press:
    Materials (rok: 2021, tom: vol. 14 iss 12 art,. no. 3419, strony: 45673), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14123419 - link to the publication
  9. Synthesis and characterization of boron carbide nanoparticles as potential boron-rich therapeutic carriers
    Authors:
    Dawid Kozień, Paulina Żeliszewska, Bożena Szermer-Olearnik, Zbigniew Adamczyk, Anna Wróblewska, Agnieszka Szczygieł, Katarzyna Węgierek-Ciura, Jagoda Mierzejewska, Elżbieta Pajtasz-Piasecka, Tomasz TOKARSKI, Grzegorz Cios, Stanisław Cudziło, Zbigniew Pędzich
    Academic press:
    Materials (rok: 2023, tom: ol. 16 iss. 19 art. no. 6534, strony: 45674), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma16196534 - link to the publication
  10. Surface Properties and Morphology of Boron Carbide Nanopowders Obtained by Lyophilization of Saccharide Precursors
    Authors:
    Dawid Kozień, Piotr Jeleń, Joanna Stępień, Zbigniew Olejniczak, Maciej Sitarz, Zbigniew Pedzich.
    Academic press:
    Materials (rok: 2021, tom: vol. 14 iss 12 art,. no. 3419, strony: 45673), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14123419 - link to the publication
  11. Boron-Rich Boron Carbide Nanoparticles as a Carrier in Boron Neutron Capture Therapy: Their Influence on Tumor and Immune Phagocytic Cells
    Authors:
    Dawid Kozień, Bożena Szermer-Olearnik, Andrzej Rapak, Agnieszka Szczygieł, Natalia Anger-Góra, Janusz Boratyński, Elżbieta Pajtasz-Piasecka, Mirosław M. Bućko, Zbigniew Pędzich.
    Academic press:
    Materials (rok: 2021, tom: vol. 14 iss. 11 art. no. 3010, strony: 45670), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14113010 - link to the publication