Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Novel polymers-based nanocarriers as radioisotope transporters for oncological theranostics

2019/33/B/ST5/02125

Keywords:

nanomaterials nanocarriers nanogels radiation synthesis radiotracers theranostics

Descriptors:

  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST5_5: Polymer materials
  • ST5_12: Methods of nanomaterials/materials synthesis

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Łódzka, Wydział Chemiczny

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Piotr Krzysztof Ulański 

Number of co-investigators in the project: 11

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 1 403 520 PLN

Project start date (Y-m-d): 2020-02-27

Project end date (Y-m-d): 2024-02-26

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (16)
  1. Synthesis and properties of targeted radioisotope carriers based on poly(acrylic acid) nanogels
    Authors:
    4) Małgorzata Matusiak, Beata P. Rurarz, Sławomir Kadłubowski, Marian Wolszczak, Urszula Karczmarczyk, Michał Maurin, Beata Kolesińska and Piotr Ulański
    Academic press:
    Pharmaceutics (rok: 2021, tom: 13, strony: Art. No. 1240), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics13081240 - link to the publication
  2. Towards cancer nanoradiopharmaceuticals—Radioisotope nanocarrier system for prostate cancer theranostics based on radiation-synthesized polymer nanogels
    Authors:
    Beata Paulina Rurarz, Kinga Anna Urbanek, Urszula Karczmarczyk, Joanna Raczkowska, Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Karolina Kowalska, Sławomir Kadłubowski, Agnieszka Sawicka, Michał Maurin, Agnieszka Wanda Piastowska-Ciesielska, Piotr Ulański
    Academic press:
    Cancers (rok: 2023, tom: 15 (23), strony: art. no. 5646), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15235646 - link to the publication
  3. Radiation synthesis of poly(acrylic acid) nanogels for drug delivery applications – post-synthesis product stability
    Authors:
    Beata P. Rurarz, Natalia Gibka, Małgorzata Bukowczyk, Sławomir Kadłubowski and Piotr Ulański
    Academic press:
    Nukleonika (rok: 2021, tom: 66(4), strony: 179-186), Wydawca: Institute of Nuclear Chemistry and Technology
    Status:
    Published
    DOI:
    10.2478/nuka-2021-0026 - link to the publication
  4. The fundamentals of polymerization reactions and modification of polymers by ionizing radiation
    Authors:
    Aiysha Ashfaq, Marie-Claude Clochard, Xavier Coqueret, Clelia Dispenza, Mark S. Driscoll, Piotr Ulański and Mohamad Al-Sheikhly
    Academic press:
    Polymers (rok: 2020, tom: 12, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym12122877 - link to the publication
  5. Nanostrategies for therapeutic and diagnostic targeting of gastrin-releasing peptide receptor
    Authors:
    Beata Paulina Rurarz, Małgorzata Bukowczyk, Natalia Gibka, Agnieszka Wanda Piastowska-Ciesielska, Urszula Karczmarczyk, Piotr Ulański
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24 (4), strony: art. no. 3455), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24043455 - link to the publication
  6. An updated review on macro, micro and nanostructured hydrogels for biomedical and pharmaceutical applications
    Authors:
    Caroline S.A. de Lima, Tatiana S. Balogh, Justine P.R.O. Varca, Gustavo H.C. Varca, Ademar B. Lugao, Luiz A. Camacho-Cruz, Emilio Bucio and Slawomir Kadlubowski
    Academic press:
    Pharmaceutics (rok: 2020, tom: 12, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics12100970 - link to the publication
  7. Nanostrategies for therapeutic and diagnostic targeting of gastrin-releasing peptide receptor
    Authors:
    Beata Paulina Rurarz, Małgorzata Bukowczyk, Natalia Gibka, Agnieszka Wanda Piastowska-Ciesielska, Urszula Karczmarczyk, Piotr Ulański
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24 (4), strony: Art. No. 3455), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24043455 - link to the publication
  8. Polymerization Reactions and Modifications of Polymers by Ionizing Radiation
    Authors:
    Aiysha Ashfaq, Marie-Claude Clochard, Xavier Coqueret, Clelia Dispenza, Mark S. Driscoll, Piotr Ulański and Mohamad Al-Sheikhly
    Academic press:
    Polymers (rok: 2020, tom: 12, strony: Art. No. 2877), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym12122877 - link to the publication
  9. Radiation synthesis of poly(acrylic acid) nanogels for drug delivery applications – post-synthesis product stability
    Authors:
    Beata P. Rurarz, Natalia Gibka, Małgorzata Bukowczyk, Sławomir Kadłubowski and Piotr Ulański
    Academic press:
    Nukleonika (rok: 2021, tom: 66(4), strony: 179-186), Wydawca: Institute of Nuclear Chemistry and Technology
    Status:
    Published
    DOI:
    10.2478/nuka-2021-0026 - link to the publication
  10. Synthesis and properties of targeted radioisotope carriers based on poly(acrylic acid) nanogels
    Authors:
    4) Małgorzata Matusiak, Beata P. Rurarz, Sławomir Kadłubowski, Marian Wolszczak, Urszula Karczmarczyk, Michał Maurin, Beata Kolesińska and Piotr Ulański
    Academic press:
    Pharmaceutics (rok: 2021, tom: 13, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics13081240 - link to the publication
  11. To be or not to be" of a polymer nanogel—Unravelling the relationship of product properties vs. synthesis conditions governing the radiation crosslinking of poly(acrylic acid) using GPC/SEC—MALLS
    Authors:
    Sławomir Kadłubowski, Beata Paulina Rurarz, Joanna Raczkowska, Carlo Dessy, Piotr Ulański
    Academic press:
    Materials (rok: 2023, tom: 16 (23), strony: art. no. 7467), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma16237467 - link to the publication
  12. An updated review on macro, micro and nanostructured hydrogels for biomedical and pharmaceutical applications
    Authors:
    Caroline S.A. de Lima, Tatiana S. Balogh, Justine P.R.O. Varca, Gustavo H.C. Varca, Ademar B. Lugao, Luiz A. Camacho-Cruz, Emilio Bucio and Slawomir Kadlubowski
    Academic press:
    Pharmaceutics (rok: 2020, tom: 12, strony: Art. No. 970), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics12100970 - link to the publication
  13. Synthesis and properties of targeted radioisotope carriers based on poly(acrylic acid) nanogels
    Authors:
    4) Małgorzata Matusiak, Beata P. Rurarz, Sławomir Kadłubowski, Marian Wolszczak, Urszula Karczmarczyk, Michał Maurin, Beata Kolesińska and Piotr Ulański
    Academic press:
    Pharmaceutics (rok: 2021, tom: 13, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics13081240 - link to the publication
  14. Radiation synthesis of poly(acrylic acid) nanogels for drug delivery applications – post-synthesis product stability
    Authors:
    Beata P. Rurarz, Natalia Gibka, Małgorzata Bukowczyk, Sławomir Kadłubowski and Piotr Ulański
    Academic press:
    Nukleonika (rok: 2021, tom: 66(4), strony: 179-186), Wydawca: Institute of Nuclear Chemistry and Technology
    Status:
    Published
    DOI:
    10.2478/nuka-2021-0026 - link to the publication
  15. The fundamentals of polymerization reactions and modification of polymers by ionizing radiation
    Authors:
    Aiysha Ashfaq, Marie-Claude Clochard, Xavier Coqueret, Clelia Dispenza, Mark S. Driscoll, Piotr Ulański and Mohamad Al-Sheikhly
    Academic press:
    Polymers (rok: 2020, tom: 12, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym12122877 - link to the publication
  16. An updated review on macro, micro and nanostructured hydrogels for biomedical and pharmaceutical applications
    Authors:
    Caroline S.A. de Lima, Tatiana S. Balogh, Justine P.R.O. Varca, Gustavo H.C. Varca, Ademar B. Lugao, Luiz A. Camacho-Cruz, Emilio Bucio and Slawomir Kadlubowski
    Academic press:
    Pharmaceutics (rok: 2020, tom: 12, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics12100970 - link to the publication