Projects funded by the NCN
The protective role of Klotho protein in the ischemia/reperfusion injury of the cardiomyocytes.
2019/33/N/NZ3/01649
Keywords:
Klotho protein ischemia/reperfusion injury cardioprotection cardiovascular disease cardiac markers
Descriptors:
- NZ3_001:
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 17 - announced on 2019-03-15
Amount awarded: 209 869 PLN
Project start date (Y-m-d): 2020-02-06
Project end date (Y-m-d): 2025-02-05
Project duration:: 60 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (3)
- Ameliorating Effect of Klotho Protein on Rat Heart during I/R InjuryAuthors:Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Marta Banaszkiewicz, and Iwona Bil-LulaAcademic press:Oxidative Medicine and Cellular Longevity (rok: 2020, tom: 2020, strony: Article ID 6427284), Wydawca: HindawiStatus:PublishedDOI:10.1155/2020/6427284 - link to the publication
- Klotho protein alleviates heart ischemia/reperfusion injury and oxidative stress through regulation of the NOS/MMP pathwayAuthors:Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Izabela Sambor, Andrzej Mysiak, Iwona Bil-LulaAcademic press:Scientific Reports (rok: 2025, tom: 15, strony: 32299), Wydawca: Springer NatureStatus:PublishedDOI:10.1038/s41598-025-18021-x - link to the publication
- Klotho Protein Decreases MMP-Mediated Degradation of Contractile Proteins during Ischaemia/Reperfusion Injury to the CardiomyocytesAuthors:Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Marta Banaszkiewicz, Iwona Bil-LulaAcademic press:International Journal of Molecular Sciences (rok: 2022, tom: 23 (24), strony: 15450), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms232415450 - link to the publication