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Information on the principal investigator and host institution

Information of the project and the call

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Metody badania białek związanych z metabolizmem końca 5' mRNA oparte na nukleotydowych sondach molekularnych

2019/32/T/ST4/00091

Keywords:

Descriptors:

  • ST4_9: Biological chemistry
  • NZ1_3: Biophysics
  • ST4_2: Spectroscopic and spectrometric techniques

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Warszawski, Wydział Fizyki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Renata Kasprzyk 

Number of co-investigators in the project: 2

Call: ETIUDA 7 - announced on 2018-12-14

Amount awarded: 115 200 PLN

Project start date (Y-m-d): 2019-10-01

Project end date (Y-m-d): 2020-09-30

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Direct High-Throughput Screening Assay for mRNA Cap Guanine- N7 Methyltransferase Activity
    Authors:
    Renata Kasprzyk, Mateusz Fido, Adam Mamot,Przemyslaw Wanat, Miroslaw Smietanski, Michal Kopcial, Victoria H. Cowling, Joanna Kowalska, and Jacek Jemielity
    Academic press:
    Chemistry - An European Journal (rok: 2020, tom: 26, strony: 11266-11275), Wydawca: Wiley-VCH
    Status:
    Published
    DOI:
    10.1002/chem.202001036 - link to the publication
  2. Enzymatic Assays to Explore Viral mRNA Capping Machinery
    Authors:
    Renata Kasprzyk, Jacek Jemielity
    Academic press:
    ChemBioChem (rok: 2021, tom: 22, strony: 3236–3253), Wydawca: Wiley-VCH
    Status:
    Published
    DOI:
    10.1002/cbic.202100291 - link to the publication
  3. Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase
    Authors:
    Renata Kasprzyk, Tomasz J. Spiewla, Miroslaw Smietanski, Sebastian Golojuch, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Johan Neyts, Joanna Kowalska, Jacek Jemielity
    Academic press:
    Antiviral Research (rok: 2021, tom: 193, strony: 105142), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.antiviral.2021.105142 - link to the publication

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