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Information of the project and the call

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Beyond simple TCR depletion model: How MHC class and sex affect trade-offs constraining MHC gene number evolution?

2019/32/C/NZ8/00440

Keywords:

evolutionary trade-offs major histocompatibility complex TCR depletion hypothesis

Descriptors:

  • NZ8_1: Evolutionary biology
  • NZ6_3: Animal immunology

Panel:

NZ8 - Evolutionary and environmental biology: evolution, ecology, population biology, biodiversity, biogeography

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Migalska 

Number of co-investigators in the project: 2

Call: SONATINA 3 - announced on 2018-12-14

Amount awarded: 899 416 PLN

Project start date (Y-m-d): 2019-11-29

Project end date (Y-m-d): 2024-05-28

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Evolutionary trade-offs constraining the MHC gene expansion: beyond simple TCR depletion model
    Authors:
    Magdalena Migalska, Kazimierz Węglarczyk, katarzyna Dudek, Joanna Homa
    Academic press:
    Frontiers in Immunology (rok: 2024, tom: 14 - 2023, strony: 1240723), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2023.1240723 - link to the publication
  2. Cross-reactivity of T cell-specific antibodies in the bank vole (Myodes glareolus)
    Authors:
    Magdalena Migalska, Kazimierz Węglarczyk, Renata Mężyk-Kopeć, Katarzyna Baliga-Klimczyk, Joanna Homa
    Academic press:
    Journal of Immunological Methods (rok: 2023, tom: 520, strony: 113524), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jim.2023.113524 - link to the publication
  3. Long term patterns of association between MHC and helminth burdens in the bank vole support Red Queen dynamics
    Authors:
    Magdalena Migalska, Karolina Przesmycka, Mohammed Alsarraf, Anna Bajer, Jolanta Behnke-Borowczyk, Maciej Grzybek, Jerzy M. Behnke, Jacek Radwan
    Academic press:
    Molecular Ecology (rok: 2022, tom: 31 (12), strony: 3400-3415), Wydawca: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1111/mec.16486 - link to the publication
  4. Coevolution between MHC class I and Antigen Processing Genes in salamanders
    Authors:
    Gemma Palomar, Katarzyna Dudek, Magdalena Migalska, J W Arntzen, G Francesco Ficetola, Dušan Jelić, Elizabeth Jockusch, Inigo Martínez-Solano, Masatoshi Matsunami, H Bradley Shaffer, Judit Vörös, Bruce Waldman, Ben Wielstra, Wiesław Babik
    Academic press:
    Molecular Biology and Evolution (rok: 2021, tom: 38, strony: 5092–5106), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/molbev/msab237 - link to the publication

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