Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The effect of phloroglucinol on the development of insulin resistance in non-alcoholic fatty liver disease (NAFLD).

2018/31/N/NZ7/03242

Keywords:

phloroglucinol insulin resistance non-alcoholic liver disease

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ4_11: Metabolism
  • NZ4_6: Endocrinology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

woj. podlaskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Krzysztof Drygalski 

Number of co-investigators in the project: 3

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2019-07-08

Project end date (Y-m-d): 2022-07-07

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Sonifikator - homogenizator ultradźwiękowy.

Information in the final report

  • Publication in academic press/journals (2)
  1. Phloroglucinol prevents albumin glycation as well as diminishes ROS production, glycooxidative damage, nitrosative stress and inflammation in hepatocytes treated with high glucose
    Authors:
    Krzysztof Drygalski, Eliza Fereniec, Anna Zalewska, Adam Krętowski, Małgorzata Żendzian-Piotrowska, Mateusz Maciejczyk
    Academic press:
    Biomedicine & Pharmacotherapy (rok: 2021, tom: 142, strony: 111958), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2021.111958 - link to the publication
  2. Phloroglucinol Strengthens the Antioxidant Barrier and Reduces Oxidative/Nitrosative Stress in Nonalcoholic Fatty Liver Disease (NAFLD)
    Authors:
    Krzysztof Drygalski, Katarzyna Siewko, Andrzej Chomentowski, Cezary Odrzygóźdź, Anna Zalewska, Adam Krętowski, Mateusz Maciejczyk
    Academic press:
    Oxidative Medicine and Cellular Longevity (rok: 2021, tom: 2021, strony: 18), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2021/8872702 - link to the publication

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