Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Investigation of parabens' estrogen-like mechanism of action in the context of assessment its influence on the functions and lifespan of human neutrophils.

2018/31/N/NZ7/01074

Keywords:

parabens neutrophils methylparaben ethylparaben propylparaben butylparaben endocrine disrupting chemicals xenoestrogens innate immunity estrogen receptors GPER

Descriptors:

  • NZ7_15: Toxicology
  • NZ6_1: Adaptive and innate immunity
  • NZ7_2: Environment and health risks

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

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Other projects carried out by the institution 

Principal investigator (from the host institution):

Karolina Nowak 

Number of co-investigators in the project: 3

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 140 000 PLN

Project start date (Y-m-d): 2019-10-02

Project end date (Y-m-d): 2021-10-01

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Investigation of estrogen-like effects of parabens on human neutrophils
    Authors:
    Karolina Nowak, Ewa Jabłońska, Marzena Garley, Agnieszka Iwaniuk, Piotr Radziwon, Sławomir Wołczyński, Wioletta Ratajczak-Wrona
    Academic press:
    Environmental Research (rok: 2022, tom: 214, strony: 113893), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.envres.2022.113893 - link to the publication
  2. NF-κB—An Important Player in Xenoestrogen Signaling in Immune Cells
    Authors:
    Karolina Nowak, Ewa Jabłońska, Wioletta Ratajczak-Wrona
    Academic press:
    Cells (rok: 2021, tom: 10, strony: 1799), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10071799 - link to the publication

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