Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Evaluation of the effects of long-term administration of new anticonvulsant drug-candidate.

2018/31/N/NZ7/02867

Keywords:

epilepsy antiepileptic drugs 1,2,4-triazole-3-thione derivatives

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Lublinie, Wydział Nauk o Zdrowiu

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Makuch-Kocka 

Number of co-investigators in the project: 3

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2019-07-22

Project end date (Y-m-d): 2023-07-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Effect of Chronic Administration of 5-(3-chlorophenyl)-4-Hexyl-2,4 -Dihydro-3H-1,2,4-Triazole-3-Thione (TP-315)—A New Anticonvulsant Drug Candidate—On Living Organisms
    Authors:
    Anna Makuch-Kocka, Marta Andres-Mach, Mirosław Zagaja, Anna Śmiech, Magdalena Pizoń, Jolanta Flieger, Judyta Cielecka-Piontek, Tomasz Plech
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 45307), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22073358 - link to the publication
  2. Spectroscopic evaluation of the potential neurotoxic effects of a new candidate for anti-seizure medication - TP-315 during chronic administration (in vivo).
    Authors:
    Mikołaj Krysa, Anna Makuch-Kocka, Katarzyna Suśniak, Tomasz Plech, Marta Andres-Mach, Mirosław Zagaja, Anna Sroka-Bartnicka.
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 45302), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23094607 - link to the publication

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