Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Bilateral interactions between WJ-MSC and fNSC affect the niche formation and regenerative abilities.

2018/31/B/NZ4/03172

Keywords:

mesenchymal stem/stromal cells fetal neural stem cells neurorestoratology neuroprotection

Descriptors:

  • NZ4_9:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Anna Otylia Sarnowska 

Number of co-investigators in the project: 6

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 867 380 PLN

Project start date (Y-m-d): 2019-10-03

Project end date (Y-m-d): 2023-10-02

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (14)
  1. Effect of long-term 3D spheroid culture on WJ-MSC
    Authors:
    Agnieszka Kaminska, Aleksandra Wedzinska, Marta Kot, Anna Sarnowska
    Academic press:
    Cells (rok: 2021, tom: 10(4), 719, strony: b.d.), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10040719 - link to the publication
  2. Deciphering the impact of cerebrospinal fluid on stem cell fate as a new mechanism to enhance clinical therapy development ral Stem Cell fate as a new hope to enhance future clinical outcome"
    Authors:
    Klaudia Radoszkiewicz, Aleksandra Bzinkowska, Magdalena Chodkowska, Paulina Rybkowska, Monika Sypecka, Ilona Zembrzuska-Kaska, and Anna Sarnowska
    Academic press:
    Frontiers in Neuroscience (rok: 2024, tom: Jan 12:17:1332751, strony: Jan 12:17:1332751), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnins.2023.1332751 - link to the publication
  3. Promising Markers in the Context of Mesenchymal Stem/Stromal Cells Subpopulations with Unique Properties
    Authors:
    Agnieszka Smolinska, Aleksandra Bzinkowska, Paulina Rybkowska, Magdalena Chodkowska, Anna Sarnowska
    Academic press:
    Stem Cell International (rok: 2023, tom: 45920, strony: 2023:1842958.), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2023/1842958 - link to the publication
  4. Stemness properties of SSEA-4+ subpopulation isolated from heterogenous Wharton's jelly mesenchymal stem/stromal cells
    Authors:
    Agnieszka Smolinska, Magdalena Chodkowska, Agata Kominek, Jakub Janiec, Katarzyna Piwocka, Dorota Sulejczak and Anna Sarnowska
    Academic press:
    Frontiers in Cell and Developmental Biology (rok: 2024, tom: Feb 22:12:1227034, strony: Feb 22:12:1227034), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcell.2024.1227034 - link to the publication
  5. Interaction of Neural Stem Cells (NSCs) and Mesenchymal Stem Cells (MSCs) as a Promising Approach in Brain Study and Nerve Regeneration.
    Authors:
    Kaminska A, Radoszkiewicz K, Rybkowska P, Wedzinska A, Sarnowska A
    Academic press:
    Cells (rok: 2022, tom: 11(9), strony: 1464), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11091464 - link to the publication
  6. Stemness properties of SSEA-4+ subpopulation isolated from heterogenous Wharton's jelly mesenchymal stem/stromal cells
    Authors:
    Agnieszka Smolinska, Magdalena Chodkowska, Agata Kominek, Jakub Janiec, Katarzyna Piwocka, Dorota Sulejczak and Anna Sarnowska
    Academic press:
    Frontiers in Cell and Developmental Biology (rok: 2024, tom: Feb 22:12:1227034, strony: Feb 22:12:1227034), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcell.2024.1227034 - link to the publication
  7. Promising Markers in the Context of Mesenchymal Stem/Stromal Cells Subpopulations with Unique Properties
    Authors:
    Agnieszka Smolinska, Aleksandra Bzinkowska, Paulina Rybkowska, Magdalena Chodkowska, Anna Sarnowska
    Academic press:
    Stem Cell International (rok: 2023, tom: 45920, strony: 2023:1842958.), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2023/1842958 - link to the publication
  8. Critical points for optimizing long-term culture and neural differentiation capacity of rodent and human neural ste
    Authors:
    Klaudia Radoszkiewicz, Valentina Hribljan, Jasmina Isakovic, Dinko Mitrecic, Anna Sarnowska
    Academic press:
    Experimental Neurology (rok: 2023, tom: 363, strony: 114353), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.expneurol.2023.114353 - link to the publication
  9. Understanding Intra- and Inter-Species Variability in Neural Stem Cells' Biology Is Key to Their Successful Cryopreservation, Culture, and Propagation.
    Authors:
    Radoszkiewicz K, Jezierska-Woźniak K, Waśniewski T, Sarnowska A.
    Academic press:
    Cells (rok: 2023, tom: Feb 2;12(3), strony: 488), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12030488 - link to the publication
  10. Understanding Intra- and Inter-Species Variability in Neural Stem Cells' Biology Is Key to Their Successful Cryopreservation, Culture, and Propagation.
    Authors:
    Radoszkiewicz K, Jezierska-Woźniak K, Waśniewski T, Sarnowska A.
    Academic press:
    Cells (rok: 2023, tom: Feb 2;12(3), strony: 488), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12030488 - link to the publication
  11. The Effect of Proinflammatory Cytokines on the Proliferation, Migration and Secretory Activity of Mesenchymal Stem/Stromal Cells (WJ-MSCs) under 5% O 2 and 21% O 2 Culture Conditions
    Authors:
    Aleksandra Wedzinska, Anna Figiel-Dabrowska, Hanna Kozlowska, Anna Sarnowska
    Academic press:
    J Clin Med . (rok: 2021, tom: Apr 21;10(9), strony: 10(9):1813), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10091813 - link to the publication
  12. Deciphering the impact of cerebrospinal fluid on stem cell fate as a new mechanism to enhance clinical therapy development ral Stem Cell fate as a new hope to enhance future clinical outcome"
    Authors:
    Klaudia Radoszkiewicz, Aleksandra Bzinkowska, Magdalena Chodkowska, Paulina Rybkowska, Monika Sypecka, Ilona Zembrzuska-Kaska, and Anna Sarnowska
    Academic press:
    Frontiers in Neuroscience (rok: 2024, tom: Jan 12:17:1332751, strony: Jan 12:17:1332751), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnins.2023.1332751 - link to the publication
  13. Effect of long-term 3D spheroid culture on WJ-MSC
    Authors:
    Agnieszka Kaminska, Aleksandra Wedzinska, Marta Kot, Anna Sarnowska
    Academic press:
    Cells (rok: 2021, tom: 10(4), 719, strony: b.d.), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10040719 - link to the publication
  14. The Effect of Proinflammatory Cytokines on the Proliferation, Migration and Secretory Activity of Mesenchymal Stem/Stromal Cells (WJ-MSCs) under 5% O 2 and 21% O 2 Culture Conditions
    Authors:
    Aleksandra Wedzinska, Anna Figiel-Dabrowska, Hanna Kozlowska, Anna Sarnowska
    Academic press:
    J Clin Med . (rok: 2021, tom: Apr 21;10(9), strony: 10(9):1813), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10091813 - link to the publication

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