Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Structure and function of fumarate-adding gltcyl radical enzymes: biochemistry, modeling and application

2018/31/F/NZ1/01856

Keywords:

glycyl radical fumarate addition benzylsuccinate anaerobic metabolism biotechnology mutagenesis QM:MM modeling

Descriptors:

  • NZ1_2:
  • NZ1_6:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Szaleniec 

Number of co-investigators in the project: 4

Call: BEETHOVEN LIFE 1 - announced on 2018-09-14

Amount awarded: 1 225 211 PLN

Project start date (Y-m-d): 2020-01-27

Project end date (Y-m-d): 2024-01-26

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Determinants for Substrate Recognition in the Glycyl Radical Enzyme Benzylsuccinate Synthase Revealed by Targeted Mutagenesis
    Authors:
    Iryna Salii, Maciej Szaleniec, Ammar Alhaj Zein, Deniz Seyhan, Anna Sekuła, Karola Schühle, Ianina Kaplieva-Dudek, Uwe Linne, Rainer U. Meckenstock, Johann Heider
    Academic press:
    ACS Catalysis (rok: 2021, tom: 11, strony: 3361−3370), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acscatal.0c04954 - link to the publication