Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

NMR structural studies of 8-17 and I-R2 DNAzymes

2018/31/D/ST4/01467

Keywords:

biomolecular NMR DNAzymes structure determination

Descriptors:

  • ST4_3:
  • ST4_4:
  • ST4_13:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii Bioorganicznej PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Witold Jacek Andrałojć 

Number of co-investigators in the project: 2

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 744 000 PLN

Project start date (Y-m-d): 2019-09-02

Project end date (Y-m-d): 2024-09-01

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Solution Structure of a Lanthanide-binding DNA Aptamer Determined Using High Quality pseudocontact shift restraints
    Authors:
    Witold Andrałojć, Julia Wieruszewska, Karol Pasternak, Zofia Gdaniec
    Academic press:
    Chemistry – A European Journal (rok: 2022, tom: 28, strony: e202202114), Wydawca: WILEY-V C H VERLAG GMBH
    Status:
    Published
    DOI:
    10.1002/chem.202202114 - link to the publication
  2. The 8-17 DNAzyme can operate in a single active structure regardless of metal ion cofactor
    Authors:
    Julia Wieruszewska, Aleksandra Pawłowicz, Ewa Połomska, Karol Pasternak, Zofia Gdaniec, Witold Andrałojć
    Academic press:
    Nature Communications (rok: 2024, tom: 15, strony: 4218), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41467-024-48638-x - link to the publication
  3. Experimental and computational investigations of RNA duplexes containing N7-regioisomers of adenosine and LNA-adenosine
    Authors:
    I. Yildirim, W. Andrałojć, A. Taghavi, D. Baranowski, Z. Gdaniec, R. Kierzek, E. Kierzek
    Academic press:
    Nucleic Acids Research (rok: 2024, tom: 53, strony: Issue 1), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkae1222 - link to the publication
  4. The oligonucleotides containing N7-regioisomer of guanosine: influence on thermodynamic properties and structure of RNA duplexes
    Authors:
    Aleksandra Jarmolowicz, Nivedita Dutta, Witold Andralojc, Joanna Sarzynska, Grzegorz Framski, Daniel Baranowski, Jerzy Boryski, Ansuman Lahiri, Zofia Gdaniec, Elzbieta Kierzek, Ryszard Kierzek
    Academic press:
    RNA (rok: 2024, tom: 31(1), strony: 86-99), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1261/rna.080106.124 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy