Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Study of immunogenic and immunoprotective activity of DNA vaccines encoding multiantigenic chimeric and fusion proteins of Toxoplasma gondii

2018/31/D/NZ6/02839

Keywords:

Toxoplasma gondii DNA vaccine fusion protein chimeric protein

Descriptors:

  • NZ6_6:
  • NZ1_1:
  • NZ1_5:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Politechnika Gdańska, Wydział Chemiczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Bartłomiej Tomasz Ferra 

Number of co-investigators in the project: 6

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 2 283 500 PLN

Project start date (Y-m-d): 2019-07-01

Project end date (Y-m-d): 2024-12-31

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. The Development of Toxoplasma gondii Recombinant Trivalent Chimeric Proteins as an Alternative to Toxoplasma Lysate Antigen (TLA) in Enzyme-Linked Immunosorbent Assay (ELISA) for the Detection of Immunoglobulin G (IgG) in Small Ruminants
    Authors:
    Bartłomiej Tomasz Ferra, Maciej Chyb, Karolina Sołowińska, Lucyna Holec-Gąsior, Marta Skwarecka, Karolina Baranowicz, Justyna Gatkowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25, strony: 45678), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25084384 - link to the publication
  2. Immunogenicity and protective efficacy of recombinant chimeric antigens based on surface proteins of Toxoplasma gondii
    Authors:
    Maciej Chyb, Bartłomiej Tomasz Ferra, Malwina Kawka, Marta Skwarecka, Bożena Dziadek, Justyna Gatkowska
    Academic press:
    Frontiers (rok: 2024, tom: 15, strony: 45672), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2024.1480349 - link to the publication
  3. Evaluation of long-term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins
    Authors:
    Chyb Maciej, Dziadek Bożena, Dzitko Katarzyna, Ferra Bartłomiej Tomasz, Kawka Malwina, Holec-Gąsior Lucyna, Gatkowska Justyna
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 45669), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-40147-z - link to the publication