Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Identification of central apparatus proteins and analysis of their role in cilia beating regulation

2018/29/B/NZ3/02443

Keywords:

cilium central pair microtubules Tetrahymena

Descriptors:

  • NZ3_1: Cell biology
  • NZ1_1: Molecular biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Joachimiak 

Number of co-investigators in the project: 5

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 1 153 600 PLN

Project start date (Y-m-d): 2019-01-21

Project end date (Y-m-d): 2023-01-20

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. kamera szybka kompatybilna z mikroskopem świetlnym.
  2. spektrofotometr do pomiaru mikroobjętości DNA/RNA (55 000 PLN)
  3. zestaw komputerowy (6 114 PLN)
  4. wytrząsarka (22 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Composition and function of the C1b/C1f region in the ciliary central apparatus
    Authors:
    Ewa Joachimiak, Anna Osinka, Hanan Farahat, Bianka Świderska, Ewa Sitkiewicz, Martyna Poprzeczko, Hanna Fabczak, Dorota Wloga
    Academic press:
    Scientific Reports (rok: 2021, tom: 11, strony: 11760), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-021-90996-9 - link to the publication
  2. PCD Genes-From Patients to Model Organisms and Back to Humans
    Authors:
    Michal Niziolek, Marta Bicka, Anna Osinka, Zuzanna Samsel, Justyna Sekretarska, Martyna Poprzeczko, Rafal Bazan, Hanna Fabczak, Ewa Joachimiak, Dorota Wloga
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 45320), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23031749 - link to the publication
  3. Ciliary Proteins: Filling the Gaps. Recent Advances in Deciphering the Protein Composition of Motile Ciliary Complexes
    Authors:
    Osinka A, Poprzeczko M, Zielinska MM, Fabczak H, Joachimiak E, Wloga D
    Academic press:
    Cells (rok: 2019, tom: 8, strony: 45313), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells8070730 - link to the publication
  4. Tubulin post-translational modifications in protists - Tiny models for solving big questions
    Authors:
    Joachimiak E, Wloga D.
    Academic press:
    Seminars in Cell and Developmental Biology (rok: 2023, tom: 137, strony: 45366), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.semcdb.2021.12.004 - link to the publication
  5. Intrinsic and Extrinsic Factors Affecting Microtubule Dynamics in Normal and Cancer Cells
    Authors:
    Filip Borys, Ewa Joachimiak, Hanna Krawczyk, Hanna Fabczak
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: 3705), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25163705 - link to the publication
  6. Central Apparatus, the Molecular Kickstarter of Ciliary and Flagellar Nanomachines
    Authors:
    Zuzanna Samsel, Justyna Sekretarska, Anna Osinka, Dorota Wloga, Ewa Joachimiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 45312), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22063013 - link to the publication
  7. Rare Human Diseases: Model Organisms in Deciphering the Molecular Basis of Primary Ciliary Dyskinesia
    Authors:
    Poprzeczko M, Bicka M, Farahat H, Bazan R, Osinka A, Fabczak H, Joachimiak E, Wloga D
    Academic press:
    Cells (rok: 2019, tom: 8, strony: 45321), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells8121614 - link to the publication

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