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Information on the principal investigator and host institution

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Evaluation of tumour metabolomic response to imatinib in a study of mouse xenograft models with gastrointestinal stromal tumour

2018/29/N/NZ7/02908

Keywords:

metabolomics gastrointestinal stromal tumours anticancer therapy imatinib

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ2_4: Metabolomics

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Szymon Macioszek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 140 000 PLN

Project start date (Y-m-d): 2019-03-01

Project end date (Y-m-d): 2023-02-28

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Multiplatform metabolomics approach for comprehensive analysis of GIST xenografts with various KIT mutations
    Authors:
    Szymon Macioszek, Danuta Dudzik, Margot Biesemans, Agnieszka Wozniak, Patrick Schoffski, and Michal J. Markuszewski
    Academic press:
    Analyst , Wydawca: The Royal Society of Chemistry
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. A Robust Method for Sample Preparation of Gastrointestinal Stromal Tumour for LC/MS Untargeted Metabolomics
    Authors:
    Szymon Macioszek, Danuta Dudzik, Julia Jacyna, Agnieszka Wozniak, Patrick Schöffski and Michał J. Markuszewski
    Academic press:
    Metabolites (rok: 2021, tom: 11, strony: 554), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo11080554 - link to the publication
  3. Metabolomic and transcriptomic response to imatinib treatment of gastrointestinal stromal tumour in xenograft-bearing mice
    Authors:
    Szymon Macioszek, Danuta Dudzik, Rafał Bartoszewski, Tomasz Stokowy , Diether Lambrechts, Bram Boeckx, Agnieszka Wozniake, Patrick Schöffski, Michał J. Markuszewski
    Academic press:
    Translational Oncology (rok: 2023, tom: 30, strony: 101632), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tranon.2023.101632 - link to the publication

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