Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Interaction of influenza virus fusion peptide with lipid membranes

2018/29/B/NZ1/02434

Keywords:

lipid membranes membrane fusion influenza virus fusion peptides computer simulations

Descriptors:

  • NZ1_4: Structural biology
  • NZ1_3: Biophysics
  • ST4_4: Theoretical and computational chemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Piotr Setny 

Number of co-investigators in the project: 4

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 1 092 200 PLN

Project start date (Y-m-d): 2019-01-31

Project end date (Y-m-d): 2023-01-30

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. 5 węzłów obliczeniowych wykorzystujących karty graficzne (80 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Two modes of fusogenic action for influenza virus fusion peptide
    Authors:
    Michał Michalski, Piotr Setny
    Academic press:
    PLOS Computational Biology , Wydawca: Public Library of Science
    Status:
    Submitted
  2. Membrane-Bound Configuration and Lipid Perturbing Effects of Hemagglutinin Subunit 2 N-Terminus Investigated by Computer Simulations
    Authors:
    Michal Michalski, Piotr Setny
    Academic press:
    Frontiers in molecular biosciences (rok: 2022, tom: 9, strony: 826366), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmolb.2022.826366 - link to the publication
  3. Transient Excursions to Membrane Core as Determinants of Influenza Virus Fusion Peptide Activity
    Authors:
    Worch Remigiusz, Dudek Anita, Borkowska Paulina, Setny Piotr
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 5301), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22105301 - link to the publication