Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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ncRNA network and epigenetic modification of cancer stem cells

2018/29/B/NZ1/01016

Keywords:

microRNA lncRNA cancer stem cells

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ3_7: Signal transduction
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agnieszka Bronisz 

Number of co-investigators in the project: 3

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 2 665 500 PLN

Project start date (Y-m-d): 2019-04-01

Project end date (Y-m-d): 2023-03-31

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Laminar.
  2. wirowka (10 000 PLN)
  3. system komputerowy (3 szt.) (45 000 PLN)
  4. inkubator (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Circular RNAs-New Kids on the Block in Cancer Pathophysiology and Management.
    Authors:
    Szczepaniak A, Bronisz A, Godlewski J.
    Academic press:
    Cells (rok: 2023, tom: 8;12(4), strony: 552), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12040552. - link to the publication
  2. Hypoxic Roadmap of Glioblastoma—Learning about Directions and Distances in the Brain Tumor Environment
    Authors:
    Agnieszka Bronisz, Elżbieta Salińska, E Antonio Chiocca, Jakub Godlewski
    Academic press:
    Cancers (Basel) (rok: 2020, tom: 13, strony: 12), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers12051213 - link to the publication
  3. MicroRNA-451 Inhibits Migration of Glioblastoma while Making It More Susceptible to Conventional Therapy
    Authors:
    Daisuke Ogawa, Khairul Ansari, Michal O Nowicki, Elżbieta Salińska, Agnieszka Bronisz, Jakub Godlewski
    Academic press:
    Non-Coding RNA (rok: 2019, tom: 5(1), 25, strony: 25), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ncrna5010025 - link to the publication
  4. Oncolytic Virus Therapy Alters the Secretome of Targeted Glioblastoma Cells.
    Authors:
    Godlewski J, Farhath M, Ricklefs FL, Passaro C, Kiel K, Nakashima H, Chiocca EA, Bronisz A
    Academic press:
    Cancers (Basel) (rok: 2021, tom: 14, strony: 13(6):1287), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13061287 - link to the publication
  5. The nuclear DICER-circular RNA complex drives the deregulation of the glioblastoma cell microRNAome
    Authors:
    A Bronisz, A K Rooj, K Krawczyński, P Peruzz, E Salińska, I Nakano, B Purow, E A Chiocca, J Godlewski
    Academic press:
    Science Advances (rok: 2020, tom: 16, strony: 6), Wydawca: AAAS
    Status:
    Published
    DOI:
    10.1126/sciadv.abc0221 - link to the publication
  6. Oxidative Stress-Part of the Solution or Part of the Problem in the Hypoxic Environment of a Brain Tumor
    Authors:
    Kamil Krawczynski, Jakub Godlewski, Agnieszka Bronisz
    Academic press:
    Antioxidants (Basel) (rok: 2020, tom: 14, strony: 9), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox9080747 - link to the publication

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