Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The role of circadian clock, Nrf2 transcription factor and haeme oxygenase in the regulation of innate immune responses. A relationship between disruption of the immune system regulation and Parkinson's Disease in the Drosophila models of PD.

2018/29/B/NZ3/02591

Keywords:

oxidative stress antimicrobial proteins dopaminergic neurons

Descriptors:

  • NZ3_4: Ageing
  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Elżbieta Pyza 

Number of co-investigators in the project: 4

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 1 262 212 PLN

Project start date (Y-m-d): 2019-01-24

Project end date (Y-m-d): 2023-07-23

Project duration:: 54 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Antimicrobial Properties of a Peptide Derived from the Male Fertility Factor kl2 Protein of Drosophila melanogaster
    Authors:
    Bernadetta Bilska, Urszula Godlewska, Milena Damulewicz , Krzysztof Murzyn , Mateusz Kwitniewski , Joanna Cichy and Elzbieta Pyza
    Academic press:
    Current issues in molecular biology (rok: 2022, tom: 44, strony: 1169-1181), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cimb44030076 - link to the publication
  2. Changes in heme oxygenase level during development affect the adult life of Drosophila melanogaster
    Authors:
    Bernadetta Bilska, Milena Damulewicz, Terence Al L. Abaquita and Elżbieta M Pyza
    Academic press:
    Frontiers in Cellular Neuroscience (rok: 2023, tom: 17, strony: 1239101), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fncel.2023.1239101 - link to the publication
  3. The dual role of heme oxygenase in regulating apoptosis in the nervous system of Drosophila melanogaster
    Authors:
    Terence Al Abaquita, Milena Damulewicz, Grzegorz Tylko, Elzbieta Pyza
    Academic press:
    Frontiers in Physiology (rok: 2023, tom: 14, strony: 1060175), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fphys.2023.1060175 - link to the publication

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