Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Characterization of secretion, composition and immune properties of the extracellular vesicles released during NLRP3 inflammasome activation, with proteomics combined with bioinformatics approach.

2018/28/C/NZ6/00069

Keywords:

non-canonical inflammasome extracellular vesicles proteomics bioinformatics

Descriptors:

  • NZ2_3: Proteomics
  • NZ6_1: Adaptive and innate immunity
  • NZ3_7: Signal transduction

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Wojciech Cypryk 

Number of co-investigators in the project: 2

Call: SONATINA 2 - announced on 2017-12-15

Amount awarded: 1 077 950 PLN

Project start date (Y-m-d): 2018-10-08

Project end date (Y-m-d): 2023-04-07

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome
    Authors:
    Sampsa Matikainen, Tuula A. Nyman and Wojciech Cypryk
    Academic press:
    Journal of Immunology (rok: 2020, tom: 204 (12), strony: 3063-9), Wydawca: The American Association of Immunologists, Inc.
    Status:
    Published
    DOI:
    10.4049/jimmunol.2000373 - link to the publication
  2. Lipopolysaccharide primes human macrophages for noncanonical inflammasome-induced extracellular vesicle secretion
    Authors:
    Wojciech Cypryk, Liliana Czernek, Katarzyna Horodecka, Jędrzej Chrzanowski, Marcin Stańczak, Katariina Nurmi, Marcelina Bilicka, Mariusz Gadzinowski, Aurelia Walczak-Drzewiecka, Maria Stensland, Kari Eklund, Wojciech Fendler, Tuula A. Nyman, Sampsa Matikainen
    Academic press:
    Journal of Immunology (rok: 2023, tom: 210, strony: 322-334), Wydawca: The American Association of Immunologists
    Status:
    Published
    DOI:
    10.4049/jimmunol.2200444 - link to the publication
  1. PROTEOMIC AND BIOINFORMATIC INVESTIGATIONS OF EXTRACELLULAR VESICLES SECRETED DURING INFLAMMATORY RESPONSE
    Authors:
    Wojciech Cypryk, Liliana Czernek, Tuula A. Nyman, Sampsa Matikainen
    Conference:
    XXIV Gliwice Scientific Meetings 2020 (rok: 2020, ), Wydawca: Association for the Support of Cancer Research Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch Silesian University of Technology
    Data:
    konferencja 20-21. listopada
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy