Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Modulation of the structure and properties of curcumin using triterpene oleanolic modifiers

2017/27/N/NZ7/02423

Keywords:

curcumin oleanolic acid chemoprevention hybrid

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Katarzyna Sowa-Kasprzak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 139 540 PLN

Project start date (Y-m-d): 2018-09-03

Project end date (Y-m-d): 2022-09-02

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Waga laboratoryjna (5 000 PLN)
  2. Automatyczna komora do derywatyzacji dla płytek Camag Derivatizer (28 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Curcumin–Triterpene Type Hybrid as Effective Sonosensitizers for Sonodynamic Therapy in Oral Squamous Cell Carcinoma
    Authors:
    Katarzyna Sowa-Kasprzak, Małgorzata Józkowiak, Dorota Olender, Anna Pawełczyk, Hanna Piotrowska-Kempisty, Lucjusz Zaprutko
    Academic press:
    Pharmaceutics (rok: 2023, tom: 15(7), strony: 2008), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics15072008 - link to the publication
  2. Synthesis of curcumin derivatives containing non-steroidal anti-inflammatory drugs
    Authors:
    Katarzyna Sowa-Kasprzak, Dorota Olender, Jacek Kujawski, Lucjusz Zaprutko, Anna Pawełczyk
    Academic press:
    Acta Poloniae Pharmaceutica - Drug Research (rok: 2023, tom: Vol. 80 No. 2, strony: ), Wydawca: Polish Pharmaceutical Society
    Status:
    Accepted for publication
    DOI:
    10.32383/appdr/161972 - link to the publication
  3. Synthesis, Cytotoxicity and Molecular Docking of New Hybrid Compounds by Combination of Curcumin with Oleanolic Acid
    Authors:
    Katarzyna Sowa-Kasprzak, Ewa Totoń, Jacek Kujawski, Dorota Olender, Natalia Lisiak, Lucjusz Zaprutko, Błażej Rubiś, Mariusz Kaczmarek, Anna Pawełczyk
    Academic press:
    Biomedicines (rok: 2023, tom: 11(6), strony: 1506), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biomedicines11061506 - link to the publication

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