Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Inflammasome as skin cancerogenesis regulator- molecular and clinical study.

2017/27/B/NZ5/02011

Keywords:

inflammasome inflammation skin cancerogenesis

Descriptors:

  • NZ5_3:
  • NZ5_9:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Aleksandra Ewa Lesiak 

Number of co-investigators in the project: 6

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 959 180 PLN

Project start date (Y-m-d): 2018-08-14

Project end date (Y-m-d): 2024-06-13

Project duration:: 70 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Ultraviolet Radiation and Chronic Inflammation—Molecules and Mechanisms Involved in Skin Carcinogenesis: A Narrative Review
    Authors:
    Ciążyńska, M.; Olejniczak-Staruch, I.; Sobolewska-Sztychny, D.; Narbutt, J.; Skibińska, M.; Lesiak, A.
    Academic press:
    Life (rok: 2021, tom: 11(4), strony: 326-340), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/life11040326 - link to the publication
  2. NLRP1 and NLRP3 inflammasomes as a new approach to skin carcinogenesis
    Authors:
    M. CIĄŻYŃSKA, I. BEDNARSKI, K. WÓDZ, J. NARBUTT, A. LESIAK
    Academic press:
    ONCOLOGY LETTERS (rok: 2020, tom: 19, strony: 1649-1656), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ol.2020.11284 - link to the publication
  3. The role of inflammasomes in cutaneous pathology
    Authors:
    M. Ciążyńska, J. Narbutt, M. Skibińska, A. Lesiak
    Academic press:
    Advances in Dermatology and Allergology (rok: 2022, tom: 1 vol. 39, strony: 39-46), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/ada.2022.113802 - link to the publication
  4. New insight into the role of the pathway NLRP1 and NLRP3 inflammasomes and IL-33 in Ultraviolet-induced cutaneous carcinogenesis
    Authors:
    Aleksandra Lesiak, Karolina Wodz, Justyna Ceryn, Dorota Sobolewska –Sztychny, Igor Bednarski, Janusz Piekarski, Marta Pabianek, Dariusz Nejc, Izabela Dróżdż, Joanna Narbutt, Marcin Noweta, Magdalena Ciazynska
    Academic press:
    Frontiers in Medicine (rok: 2025, tom: 11, strony: 46029), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fmed.2024.1483208 - link to the publication

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