Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Vitamin D effects on macrophages and fibroblasts accompanying the breast cancer

2017/27/B/NZ5/01167

Keywords:

breast cancer macrophages fibroblasts TAMs CAFs vitamin D3 calcitriol

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ5_3: Pathogenesis of human diseases
  • NZ4_12: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Joanna Wietrzyk 

Number of co-investigators in the project: 17

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 1 716 680 PLN

Project start date (Y-m-d): 2018-09-26

Project end date (Y-m-d): 2022-09-25

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Autoklaw.
  2. Mikroskop wyposażony w kamerę i oprogramowanie do analizy morfometrycznej obrazu. (70 000 PLN)
  3. Zamrażarka -80 (58211 PLN) oraz zamrażarka -20oC (1000PLN) (59 211 PLN)
  4. Termomikser.

Information in the final report

  • Publication in academic press/journals (2)
  1. Modulation of fibroblast activity via vitamin D3 is dependent on tumor type—studies on mouse mammary gland cancer
    Authors:
    Natalia Łabędź, Martyna Stachowicz-Suhs, Mateusz Psurski, Artur Anisiewicz, Joanna Banach, Aleksandra Piotrowska, Piotr Dziegiel, Adam Maciejczyk, Rafał Matkowski, Joanna Wietrzyk
    Academic press:
    Cancers (rok: 2022, tom: 14, strony: 4585), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14194585 - link to the publication
  2. Vitamin D Metabolite Profile in Cholecalciferol- or Calcitriol-Supplemented Healthy and Mammary Gland Tumor-Bearing Mice
    Authors:
    Artur Anisiewicz, Konrad Kowalski, Joanna Banach, Natalia Łabędź, Martyna Stachowicz-Suhs, Aleksandra Piotrowska, Magdalena Milczarek, Dagmara Kłopotowska, Piotr Dzięgiel and Joanna Wietrzyk
    Academic press:
    Nutrients (rok: 2020, tom: 12, strony: 3416), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu12113416 - link to the publication

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