Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The sensitization of pancreatic cancer cells to pulsed electric field and electrochemotherapy - from molecular modeling to miniaturized 3D cell cultures

2017/27/N/NZ3/01110

Keywords:

electrochemotherapy electroporation pancreatic cancer antyoxidant prooxidant

Descriptors:

  • NZ3_1: Cell biology
  • NZ1_2: Biochemistry
  • NZ5_7: Human disease treatment

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Olga Michel 

Number of co-investigators in the project: 2

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 209 500 PLN

Project start date (Y-m-d): 2018-08-23

Project end date (Y-m-d): 2022-08-22

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Notebook (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. Electropermeabilization does not correlate with plasma membrane lipid oxidation
    Authors:
    Olga Michel, Andrei G. Pakhomov, Maura Casciola, Jolanta Saczko, Julita Kulbacka, Olga N. Pakhomova
    Academic press:
    Bioelectrochemistry (rok: 2020, tom: 132, strony: 107433), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2019.107433 - link to the publication
  2. Chemotherapy and Physical Therapeutics Modulate Antigens on Cancer Cells
    Authors:
    Wojciech Szlasa, Natalia Janicka, Natalia Sauer, Olga Michel, Bernadetta Nowak, Jolanta Saczko, Julita Kulbacka
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 13, strony: Artykuł 889950), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.889950 - link to the publication
  3. Nanosecond pulsed electric field suppresses growth and reduces multi‑drug resistance effect in pancreatic cancer
    Authors:
    Wojciech Szlasa, Olga Michel, Natalia Julia Sauer, Vitalij Novickij, Damian Lewandowski, Paulina Kasperkiewicz, Mounir Tarek, Jolanta Saczko, Julita Kulbacka
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: Artykuł 351), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-023-27605-4 - link to the publication
  4. The role of catechin in electroporation of pancreatic cancer cells – Effects on pore formation and multidrug resistance proteins
    Authors:
    Olga Michel, Wojciech Szlasa, Dagmara Baczyńska, Jolanta Saczko, Mounir Tarek, Julita Kulbacka
    Academic press:
    Bioelectrochemistry (rok: 2022, tom: 147, strony: Artykuł 108199), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2022.108199 - link to the publication
  1. Unravelling the mechanisms of the increased efficacy of electrochemotherapy after catechin incubation in pancreatic cancer
    Authors:
    Olga Michel , Wojciech Szlasa , Mounir Tarek, Jolanta Saczko, Julita Kulbacka
    Conference:
    4th International Wroclaw Scientific Meetings (rok: 2020, ), Wydawca: Wydawnictwo Naukowe TYGIEL sp. z o.o.
    Data:
    konferencja 09-10.10.2020
    Status:
    Published
    DOI:
    link to the publication

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