Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Peptide foldamer-based nanostructures

2017/26/D/ST5/00341

Keywords:

bionanomaterials foldamer helix beta-sheet beta-hairpin

Descriptors:

  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_12: Methods of nanomaterials/materials synthesis

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Wrocławska

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Monika Szefczyk 

Number of co-investigators in the project: 2

Call: SONATA 13 - announced on 2017-06-14

Amount awarded: 630 500 PLN

Project start date (Y-m-d): 2018-06-04

Project end date (Y-m-d): 2021-12-03

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Waga analityczna (8 000 PLN)
  2. Wyparka rotacyjna z pompą membranową (28 000 PLN)
  3. Zamrażarka niskotemperaturowa.
  4. Suszarka laboratoryjna (6 000 PLN)
  5. Komputer osobisty (5 000 PLN)
  6. Licencja do użytkowania CHARMMa (3 500 PLN)
  7. Miniwirówka typu Eppendorf (7 000 PLN)
  8. Automatyczny system do miareczkowania.
  9. Liofilizator laboratoryjny z pompą olejową i zestawem naczyń do liofilizacji (52 000 PLN)
  10. Lodówkozamrażarka (2 000 PLN)
  11. Mieszadło magnetyczne z funkcją grzania (4 000 PLN)
  12. Preparatywna kolumna chromatograficzna do HPLC wraz z przedkolumną dedykowane do peptydów (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (1)
  1. Hierarchical Approach for the Rational Construction of Helix-Containing Nanofibrils Using α,β-Peptides
    Authors:
    M. Szefczyk, N. Szulc, M. Gąsior-Głogowska, A.Modrak-Wójcik, A. Bzowska, W. Majstrzyk, M. Taube, M. Kozak, T. Gotszalk, E. Rudzińska-Szostak, Ł. Berlicki
    Academic press:
    Nanoscale (rok: 2021, tom: 13, strony: 4000-4015), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/D0NR04313C - link to the publication
  2. Peptide foldamer-based self-assembled nanostructures containing cyclic beta-amino acids
    Authors:
    M. Szefczyk
    Academic press:
    Nanoscale (rok: 2021, tom: 13, strony: 11325-11333), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/D1NR02220B - link to the publication
  3. Searching for universal model of amyloid signaling motifs using probabilistic context-free grammars
    Authors:
    W. Dyrka, M. Gąsior-Głogowska, M. Szefczyk, N. Szulc
    Academic press:
    BMC Bioinformatics (rok: 2021, tom: 22, strony: 222), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12859-021-04139-y - link to the publication
  4. Controlling the conformational stability of coiled-coil peptides by a single stereogenic center of peripheral β-amino acid residue
    Authors:
    M. Szefczyk, K. Ożga, M. Drewniak-Świtalska, E. Rudzińska-Szostak, R. Hołubowicz, A. Ożyhar, Ł. Berlicki
    Academic press:
    RSC Advances (rok: 2022, tom: 12, strony: 4640-4647), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/D2RA00111J - link to the publication
  5. Variability of amyloid propensity in imperfect repeats of CsgA protein of Salmonella enterica and Escherichia coli
    Authors:
    N. Szulc, M. Gąsior-Głogowska, J. W. Wojciechowski, M. Szefczyk, A. Żak, M. Burdukiewicz, M. Kotulska
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 5127), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22105127 - link to the publication
  1. Challenges in experimental methods
    Authors:
    M. E. Gąsior-Głogowska, N. Szulc, M. Szefczyk
    Book:
    Computer Simulations of Aggregation of Proteins and Peptides. Methods in Molecular Biology (rok: 2022, tom: 2340, strony: 281-307), Wydawca: Humana
    Status:
    Published