Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Application of metagenomics for the detection of pathogens in patients with encephalitis and meningitis

2017/25/B/NZ6/01463

Keywords:

metagenomics next-generation sequencing encephalitis meningitis

Descriptors:

  • NZ6_5: Virology
  • NZ6_4: Bacteriology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Tomasz Laskus 

Number of co-investigators in the project: 3

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 838 800 PLN

Project start date (Y-m-d): 2018-01-24

Project end date (Y-m-d): 2023-01-23

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  1. Enteroviral central nervous system infections in patients with Lyme neuroborreliosis
    Authors:
    Karol Perlejewski Marek Radkowski Agnieszka Pawełczyk Małgorzata Rydzanicz Tomasz Dzieciątkowski Michał Makowiecki Marcin Paciorek Renata Welc-Falęciak Andrzej Horban Tomasz Laskus
    Academic press:
    Ticks and Tick-borne Diseases (rok: 2023, tom: 14, strony: 45664), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ttbdis.2023.102253 - link to the publication
  2. Metagenomic search of viral coinfections in herpes simplex encephalitis patients
    Authors:
    Karol Perlejewski Marek Radkowski Małgorzata Rydzanicz Tomasz Dzieciątkowski Steffi Silling Magdalena Wieczorek Michał Makowiecki Andrzej Horban Tomasz Laskus
    Academic press:
    J Nourovirol. (rok: 2023, tom: 29 (5), strony: 588-597.), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s13365-023-01157-9 - link to the publication
  3. Search for Viral Infections in Cerebrospinal Fluid From Patients With Autoimmune Encephalitis.
    Authors:
    Perlejewski K, Pawełczyk A, Bukowska-Ośko I, Rydzanicz M, Dzieciątkowski T, Paciorek M, Makowiecki M, Caraballo Cortés K, Grochowska M, Radkowski M, Laskus T.
    Academic press:
    Open Forum Infect Dis. (rok: 2020, tom: 7(11), strony: 468), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/ofid/ofaa468. - link to the publication
  4. Human Pegivirus in Patients with Encephalitis of Unclear Etiology, Poland
    Authors:
    Iwona Bukowska-Ośko, Karol Perlejewski,corresponding author Agnieszka Pawełczyk, Małgorzata Rydzanicz, Agnieszka Pollak, Marta Popiel, Kamila Caraballo Cortés, Marcin Paciorek, Andrzej Horban, Tomasz Dzieciątkowski, Marek Radkowski, and Tomasz Laskus
    Academic press:
    Emerg Infect Dis. (rok: 2018, tom: 24(10), strony: 1785-1794), Wydawca: CDC
    Status:
    Published
    DOI:
    10.180161 - link to the publication
  5. Contamination Issue in Viral Metagenomics: Problems, Solutions, and Clinical Perspectives
    Authors:
    Henryk Jurasz, Tomasz Pawłowski and Karol Perlejewski
    Academic press:
    Front. Microbiol., 20 October 2021 | https://doi.org/10.3389/fmicb.2021.745076 (rok: 2021, tom: 11, strony: 745076-82), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2021.745076 - link to the publication
  6. Search for viral agents in cerebrospinal fluid in patients with multiple sclerosis using real-time PCR and metagenomics.
    Authors:
    Perlejewski K, Bukowska-Ośko I, Rydzanicz M, Dzieciątkowski T, Zakrzewska-Pniewska B, Podlecka-Piętowska A, Filipiak A, Barć K, Caraballo Cortés K, Pawełczyk A, Radkowski M, Laskus T.
    Academic press:
    PlosONE (rok: 2020, tom: Oct 28;15(10), strony: e0240601), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0240601. - link to the publication
  7. Next-generation sequencing in the diagnosis of viral encephalitis: sensitivity and clinical limitations.
    Authors:
    Perlejewski K, Bukowska-Ośko I, Rydzanicz M, Pawełczyk A, Caraballo Cortѐs K, Osuch S, Paciorek M, Dzieciątkowski T, Radkowski M, Laskus T.
    Academic press:
    Sci Rep (rok: 2020, tom: 10(1), strony: 16173), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-020-73156-3. - link to the publication
  8. Patients with Infections of The Central Nervous System Have Lowered Gut Microbiota Alpha Diversity
    Authors:
    Marta Grochowska, Tomasz Laskus, Marcin Paciorek, Agnieszka Pollak, Urszula Lechowicz, Michał Makowiecki, Andrzej Horban, Marek Radkowski, Karol Perlejewski
    Academic press:
    Curr Issues Mol Biol (rok: 2022, tom: 44(7), strony: 2903-2914.), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cimb44070200. - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy