Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The role of Rbs1 protein in control of general response to defect in tRNA biosynthesis in yeast Saccharomyces cerevisiae

2017/25/B/NZ1/01889

Keywords:

yeast tRNA RNA polymerase III Gcn4 transcription factor

Descriptors:

  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Magdalena Rakowska-Boguta 

Number of co-investigators in the project: 5

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 957 600 PLN

Project start date (Y-m-d): 2018-01-10

Project end date (Y-m-d): 2022-01-09

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (4)
  1. Assembly of RNA polymerase III complex involves a putative co-translational mechanism
    Authors:
    Boguta M
    Academic press:
    Gene (rok: 2022, tom: 824, strony: 146394), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.gene.2022.146394 - link to the publication
  2. Rbs1 protein, involved in RNA polymerase III complex assembly in the yeast Saccharomyces cerevisiae, induces a Gcn4 response and forms aggregates when overproduced
    Authors:
    Rudzińska I, Płonka M, Armatowska A, Turowski TW, Boguta M.
    Academic press:
    Gene (rok: 2022, tom: 809, strony: 146034), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.gene.2021.146034 - link to the publication
  3. Reprogramming mRNA Expression in Response to Defect in RNA Polymerase III Assembly in the Yeast Saccharomyces cerevisiae
    Authors:
    Rudzińska I, Cieśla M, Turowski TW, Armatowska A, Turowski TW, Leśniewska E, Boguta M
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 7298), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22147298 - link to the publication
  4. Specific Features of RNA Polymerases I and III: Structure and Assembly
    Authors:
    Turowski TW and Boguta M
    Academic press:
    Frontiers in Molecular Biosciences (rok: 2021, tom: 8, strony: 680090), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fmolb.2021.680090 - link to the publication
  5. The expression of Rpb10, a small subunit common to RNA polymerases, is modulated by the R3H domain-containing Rbs1 protein and the Upf1 helicase
    Authors:
    Cieśla M, Turowski TW, Nowotny M, Tollervey D, Boguta M
    Academic press:
    Nucleic Acids Research (rok: 2020, tom: 48, strony: 12252-12268), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkaa1069 - link to the publication
  1. The R3H domain-containing Rbs1 protein and the Upf1 helicase modulate the expression of Rpb10, a small subunit common to RNA polymerases
    Authors:
    Cieśla M, Boguta M.
    Conference:
    OddPols 2021: International Conference on Transcription Mechanism and Regulation (rok: 2021, ), Wydawca: University of Denver, Colorado, USA
    Data:
    konferencja 14-18 czerwca
    Status:
    Published
  2. Defect in RNA polymerase III assembly in yeast Saccharomyces cerevisiae results in reprogramming of mRNA expression
    Authors:
    Rudzińska I, Cieśla M, Turowski T, Armatowska A, Leśniewska E, Boguta M.
    Conference:
    OddPols 2021: International Conference on Transcription Mechanism and Regulation (rok: 2021, ), Wydawca: University of Denver, Colorado, USA
    Data:
    konferencja 14-18 czerwiec
    Status:
    Published
  3. R3H domain-containing Rbs1 protein interacts with Upf1 helicase and modulates the expression of Rpb10, a small subunit common to RNA polymerases
    Authors:
    Cieśla M., Nowotny M., Boguta M.,
    Conference:
    The 25th Annual Meeting of the RNA Society (rok: 2020, ), Wydawca: The RNA Society
    Data:
    konferencja 26-31 Maja
    Status:
    Published
  4. Reprogramming of mRNA expression in response to a defect in RNA polymerase III assembly in yeast Saccharomyces cerevisiae
    Authors:
    Rudzińska I., Cieśla M., Armatowska A., Boguta M.,
    Conference:
    The 25th Annual Meeting of the RNA Society (rok: 2020, ), Wydawca: The RNA Society
    Data:
    konferencja 26-31 Maja
    Status:
    Published