Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Mechanism of NF-kB activation in preeclamptic placentas

2017/25/B/NZ5/01961

Keywords:

placenta NF-kB preeclampsia

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agata Sakowicz 

Number of co-investigators in the project: 4

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 546 000 PLN

Project start date (Y-m-d): 2018-01-19

Project end date (Y-m-d): 2022-01-18

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. System do detekcji materiałów znakowanych chemiluminescency jnie wraz z oprogramowaniem (138 990 PLN)
  2. Stacja robocza do pracy w warunkach hipoksji (180 400 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. The Targeting of Nuclear Factor Kappa B by Drugs Adopted for the Prevention and Treatment of Preeclampsia
    Authors:
    Sakowicz A
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 2881), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23052881 - link to the publication
  2. Canonical, Non-Canonical and Atypical Pathways of Nuclear Factor кb Activation in Preeclampsia
    Authors:
    Agata Sakowicz, Michalina Bralewska, Tadeusz Pietrucha, Dominika E Habrowska-Górczyńska, Agnieszka W Piastowska-Ciesielska, Agnieszka Gach, Magda Rybak-Krzyszkowska, Piotr J Witas, Hubert Huras, Mariusz Grzesiak and Lidia Biesiada
    Academic press:
    International Journal of Molecular Science (rok: 2020, tom: 21 (15), strony: 5574), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21155574 - link to the publication
  3. The Preeclamptic Environment Promotes the Activation of Transcription Factor Kappa B by P53/RSK1 Complex in a HTR8/SVneo Trophoblastic Cell Line
    Authors:
    Agata Sakowicz, Michalina Bralewska, Tadeusz Pietrucha, Francesc Figueras, Dominika E. Habrowska-Górczyńska, Agnieszka W. Piastowska-Ciesielska, Agnieszka Gach, Bartosz Sakowicz, Magda Rybak-Krzyszkowska, Hubert Huras, Mariusz Grzesiak, Lidia Biesiada
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 10200), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms221910200 - link to the publication
  1. Nuclear Factor Kappa B (NFĸB) Activation Pathways in Preeclampsia
    Authors:
    Agata Sakowicz, Michalina Bralewska, Dominika E. Habrowska-Górczyńska, Agnieszka W. Piastowska- Ciesielska, Piotr J. Witas, Magda Rybak-Krzyszkowska, Hubert Huras, Agnieszka Gach, Tadeusz Pietrucha, Bartosz Sakowicz, Mariusz Grzesiak, Lidia Biesiada
    Conference:
    6th International Congress on Cardiac Problems in Pregnancy (rok: 2021, ), Wydawca: brak danych
    Data:
    konferencja 11-14 luty
    Status:
    Published

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