Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The effect of the peripheral and central administration of caffeine on the activity of hypothalamic-pituitary unit of ewe in the follicular phase of the estrous cycle during the physiological state and immune stress

2017/25/B/NZ9/00225

Keywords:

caffeine GnRH luteinizing hormone inflammation stress ewe

Descriptors:

  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Andrzej Herman 

Number of co-investigators in the project: 10

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 326 850 PLN

Project start date (Y-m-d): 2018-01-03

Project end date (Y-m-d): 2023-01-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (4)
  1. Effect of Caffeine on the Inflammatory-Dependent Changes in the GnRH/LH Secretion in a Female Sheep Model
    Authors:
    Andrzej Przemysław Herman, Monika Tomczyk, Maciej Wójcik, Joanna Bochenek, Hanna Antushevich, Anna Herman, Wiktoria Wiechetek Aleksandra Szczepkowska, Elżbieta Marciniak, Dorota Tomaszewska-Zaremba
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25(5), strony: 2663), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25052663 - link to the publication
  2. Inflammation induced by endotoxin from Escherichia coli enables the central action of caffeine on GnRH/LH secretion in a female sheep
    Authors:
    Andrzej Przemysław Herman, Maciej Wójcik, Monika Tomczyk, Joanna Bochenek, Hanna Antushevich, Anna Herman, Aleksandra Szczepkowska, Elżbieta Marciniak, Dorota Tomaszewska-Zaremba
    Academic press:
    VETERINARY RESEARCH , Wydawca: Springer Nature
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Effect of caffeine on adenosine and ryanodine receptor gene expression in the hypothalamus, pituitary, and choroid plexus in ewes under basal and LPS challenge conditions
    Authors:
    A. Szczepkowska, J. Bochenek, M. Wójcik, D. Tomaszewska-Zaremba, H. Antushevich, M. Tomczyk, J. Skipor, A. P. Herman
    Academic press:
    Journal of Animal and Feed Sciences (rok: 2023, tom: 32, strony: 17–25), Wydawca: Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN
    Status:
    Published
    DOI:
    10.22358/jafs/156762/2022 - link to the publication
  4. Acute Effect of Caffeine on the Synthesis of Pro-Inflammatory Cytokines in the Hypothalamus and Choroid Plexus during Endotoxin-Induced Inflammation in a Female Sheep Model
    Authors:
    Aleksandra Szczepkowska, Maciej Wójcik, Dorota Tomaszewska-Zaremba, Hanna Antushevich,2 Agata Krawczyńska, Wiktoria Wiechetek, Janina Skipor, and Andrzej Przemysław Herman
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 22(24), strony: 13237), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222413237 - link to the publication
  1. The effect of central injection of caffeine on GnRH/LH secretion in follicular phase ewes during an immune/inflammatory challenge
    Authors:
    Monika Tomczyk, Joanna Bochenek, Maciej Wójcik, Wiktoria Wiechetek, Anna Antushevich, Dorota Tomaszewska-Zaremba, Anna Herman, Andrzej P. Herman
    Conference:
    VI Zjazd Polskiego Towarzystwa Neuroendokrynologii (rok: 2022, ), Wydawca: Polskie Towarzystwo Neuroendokrynologii
    Data:
    konferencja 18–19 listopada 2022
    Status:
    Published
  2. Influence of caffeine on the secretion of GnRH/LH during an immune/inflammatory challenge in follicular phase ewes
    Authors:
    Andrzej Przemysław Herman, Maciej Wójcik, Monika Tomczyk, Joanna Bochenek, Karolina Wojtulewicz, Agata Krawczyńska, Hanna Antushevich, Elżbieta Marciniak, Wiktoria Wiechetek, Dorota Tomaszewska-Zaremba
    Conference:
    IX ZJAZD TOWARZYSTWA BIOLOGII ROZRODU (rok: 2021, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 2-4.09.2021
    Status:
    Published
  3. Influence of caffeine on the gene expression of proinflammatory cytokines and their receptors in the hypothalamic-pituitary unit
    Authors:
    M. Wójcik, M. Tomczyk, J. Bochenek, D. Tomaszewska-Zaremba, A. Antushevich, A. Krawczyńska, A. Herman, A.P. Herman
    Conference:
    XXVIII Congress of the Polish Society of Physiology (rok: 2021, ), Wydawca: Polish Physiological Society
    Data:
    konferencja 15-17.09.2021
    Status:
    Published
  4. PERIPHERAL ADMINISTRATION OF CAFFEINE INFLUENCES THE SYNTHESIS OF GNRH AND LUTEINIZING HORMONE IN EWE DURING THE FOLLICULAR PHASE OF THE ESTROUS CYCLE
    Authors:
    Monika Tomczyk, Maciej Wójcik, Joanna Bochenek, Bartosz Pawlina, Dorota Tomaszewska-Zaremba, Anna Antushevich, Agata Krawczyńska, Anna Herman, Andrzej Przemysław Herman
    Conference:
    The 5th Winter Workshop of the Society for Biology of Reproduction "Central and Local Regulations of Reproductive Processes" (rok: 2019, ), Wydawca: Instytut Zootechniki - Państwowy Instytut Badawczy
    Data:
    konferencja 13-15.02.2019
    Status:
    Published

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