Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effect of inhalation dynamics on the aerosolization, transport and deposition of aerosol drugs emitted from the passive Dry Powder Inhaler.

2017/25/N/ST8/00809

Keywords:

particle size characteristics aerosol emission kinetics deposition distribution unsteady flow passive Dry Powder Inhaler

Descriptors:

  • ST8_4: Fluid mechanics, technical thermodynamics

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Warszawska, Wydział Inżynierii Chemicznej i Procesowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agata Dorosz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 119 600 PLN

Project start date (Y-m-d): 2018-03-05

Project end date (Y-m-d): 2022-03-04

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mieszający port wlotowy do impaktora nowej generacji (NGI) (Copley Scientific, UK) (30 000 PLN)
  2. Stacjonarny konduktometr laboratoryjny (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  • Book publications / chapters in book publications (1)
  1. Dynamics of aerosol generation and release - Dry Powder Inhaler performance considerations
    Authors:
    Agata Dorosz, Marta Zaczek, Arkadiusz Moskal
    Academic press:
    Journal of Aerosol Science (rok: 2021, tom: 151, strony: 105673), Wydawca: Elsevier Ltd.
    Status:
    Published
    DOI:
    10.1016/j.jaerosci.2020.105673 - link to the publication
  2. Inhalation profiles through a dry powder inhaler: relation with inhalation technique and spirometric measures
    Authors:
    Dorosz, Agata, Urbankowski, Tomasz, Zieliński, Krzysztof, Michnikowski, Marcin, Krenke, Rafał, Moskal, Arkadiusz
    Academic press:
    Journal of Aerosol Medicine and Pulmonary Drug Delivery (rok: 2021, tom: 34, strony: 346-357), Wydawca: Mary Ann Liebert Inc.
    Status:
    Published
    DOI:
    10.1089/jamp.2020.1663 - link to the publication
  3. Modeling of Inhalation Profiles Through Dry Powder Inhaler in Healthy Adults and Asthma Patients As a Prerequisite for Further In Vitro and In Silico Studies
    Authors:
    Dorosz, Agata, Urbankowski, Tomasz, Zieliński, Krzysztof, Michnikowski, Marcin, Krenke, Rafał, Moskal, Arkadiusz
    Academic press:
    Journal of Aerosol Medicine and Pulmonary Drug Delivery (rok: 2022, tom: 35, strony: 91-104), Wydawca: Mary Ann Liebert Inc.
    Status:
    Published
    DOI:
    10.1089/jamp.2021.0021 - link to the publication
  1. Time-dependent Aerosolization Characteristics and Emission Kinetics of Dry Powder Inhaler Formulations
    Authors:
    Agata Dorosz, Marta Zaczek, Arkadiusz Moskal
    Conference:
    Respiratory Drug Delivery Europe 2019 (rok: 2019, ), Wydawca: Virginia Commonwealth University
    Data:
    konferencja 43592
    Status:
    Published
  1. Cascade impactor study of aerosolization process during passive dry powder inhaler performance under unsteady versus steady flow conditions
    Authors:
    Dorosz Agata, Martínez Cánovas Paula, Moskal Arkadiusz
    Book:
    Practical Aspects of Chemical Engineering - Selected Contributions from PAIC 2019 (rok: 2020, tom: n.a., strony: 47-57), Wydawca: Springer International Publishing
    Status:
    Published