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Identification of molecular mechanisms responsible for the MMP-9-1562C/T- dependent differential regulation of Matrix Metalloproteinase-9 expression in human neurons.

2017/25/N/NZ3/02266

Keywords:

Matrix Metalloproteinase-9 (MMP-9) polymorphism transcription factors neurons

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Centrum Medyczne Kształcenia Podyplomowego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Sylwia Pabian-Jewuła 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 179 556 PLN

Project start date (Y-m-d): 2018-02-06

Project end date (Y-m-d): 2023-02-05

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  • Book publications / chapters in book publications (1)
  1. Identification of Molecular Mechanisms Responsible for the MMP-9-1562C/T Dependent Differential Regulation of Matrix Metalloproteinase-9 Expression in Human Neuron-like Cells
    Authors:
    Sylwia Pabian-Jewuła * , Magdalena Ambrożek-Latecka , Aneta Brągiel-Pieczonka , Klaudia Nowicka , Marcin Rylski*
    Academic press:
    Genes (rok: 2023, tom: 14, strony: 2028), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes14112028 - link to the publication
  2. Does the functional polymorphism -1562C/T of MMP-9 gene influences brain disorders?
    Authors:
    Sylwia Pabian-Jewuła, Marcin Rylski
    Academic press:
    Frontiers in Cellular Neuroscience (rok: 2023, tom: 17, strony: 1110967), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fncel.2023.1110967 - link to the publication
  3. Ying Yang 1 engagement in brain pathology
    Authors:
    Sylwia Pabian-Jewuła, Aneta Bragiel-Pieczonka, Marcin Rylski
    Academic press:
    Journal of Neurochemistry (rok: 2022, tom: 10,1111, strony: 15594), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1111/jnc.15594 - link to the publication
  1. Mechanism of MMP-9-1562C/T single nucleotide polymorphism-dependent regulation of MMP-9 (Matrix Metaloproteinase-9) expression in human neurons
    Authors:
    Pabian-Jewuła S1 , Ambrożek-Latecka M2 , Rylski M3
    Conference:
    Virtual FENS Regional Meeting 2021 (rok: 2021, ), Wydawca: FENS
    Data:
    konferencja 25-27.08
    Status:
    Published
  1. Czy funkcjonalny polimorfizm genu MMP-9-1562C/T wpływa na choroby mózgu?
    Authors:
    Pabian-Jewuła Sylwia
    Book:
    Postępy i zagadnienia nauk medycznych i przyrodniczych (rok: 2021, tom: I, strony: 43-50), Wydawca: Bogucki Wydawnictwo Naukowe, 2021
    Status:
    Published

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