Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Phthalimide derivatives of porphyrazines incorporated into liposomes as potential candidates for photodynamic therapy

2017/25/N/NZ7/01705

Keywords:

phthalimide photodynamic therapy porphyrazine synthesis liposomes

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Michał Falkowski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 180 000 PLN

Project start date (Y-m-d): 2018-01-25

Project end date (Y-m-d): 2023-01-24

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mieszadło magnetyczne firmy Heidolph wraz z nakładkami Heat-on (5 800 PLN)
  2. Pompa próżniowa V-100 z kontrolerem próżni I-100 firmy BÜCHI (12 300 PLN)
  3. Termostat cyrkulacyjny Minichiller w firmy Huber (15 500 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (6)
  1. Improved Electrochemical Hydrogen Peroxide Detection Using a Nickel(II) Phthalimide-Substituted Porphyrazine Combined with Various Carbon Nanomaterials
    Authors:
    Amanda Leda, Mina Hassani, Tomasz Rebis, Michal Falkowski, Jaroslaw Piskorz, Dariusz T Mlynarczyk, Peter McNeice, Grzegorz Milczarek
    Academic press:
    Nanomaterials (rok: 2023, tom: 13, 862, strony: 45305), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano13050862 - link to the publication
  2. Synthesis of sulfanyl porphyrazines with bulky peripheral substituents – Evaluation of their photochemical properties and biological activity
    Authors:
    Michal Falkowski, Malgorzata Kucinska, Jarosław Piskorz, Ewelina Wieczorek-Szweda, Lukasz Popenda, Stefan Jurga, Adam Sikora, Dariusz T. Młynarczyk, Marek Murias, Michal P. Marszall, Tomasz Goslinski
    Academic press:
    Journal of Photochemistry and Photobiology A: Chemistry (rok: 2021, tom: 405, strony: 112964), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jphotochem.2020.112964 - link to the publication
  3. A synergistic effect of phthalimide-substituted sulfanyl porphyrazines and carbon nanotubes to improve the electrocatalytic detection of hydrogen peroxide
    Authors:
    Michal Falkowski, Amanda Leda, Tomasz Rebis, Jaroslaw Piskorz, Lukasz Popenda, Mina Hassani, Dariusz T Mlynarczyk, Michal P Marszall, Grzegorz Milczarek
    Academic press:
    Molecules (rok: 2022, tom: 27, 4409, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    https://www.mdpi.com/1420-3049/27/14/4409 - link to the publication
  1. A Metallated sulfanyl porphyrazines possessing phthalimid substituents – electrochemical properties and synergic effect with nanomaterial components
    Authors:
    Michal Falkowski, Lukasz Popenda, Tomasz Rebis, Jaroslaw Piskorz, Dariusz T. Mlynarczyk, Stefan Jurga, Michal P. Marszall, Adam Sikora, Jadwiga Mielcarek, Grzegorz Milczarek, Tomasz Goslinski
    Conference:
    NanoTech Poland & 1st Symposium on Polydopamine (rok: 2018, ), Wydawca: NanoBioMedical Centre, Adam Mickiewicz University in Poznan
    Data:
    konferencja 6-9 czerwca
    Status:
    Published
  2. Synthesis of phthalimide sulfanyl porphyrazines and their optical properties
    Authors:
    Michal Falkowski, Lukasz Popenda, Jaroslaw Piskorz, Ewelina Wieczorek, Stefan Jurga, Michal P. Marszall, Dominik Mieszkowski, Jadwiga Mielcarek, Tomasz Goslinski
    Conference:
    NanoTech Poland & 1st Symposium on Polydopamine (rok: 2018, ), Wydawca: NanoBioMedical Centre, Adam Mickiewicz University in Poznan
    Data:
    konferencja 6-9 czerwca
    Status:
    Published
  3. Synthesis of sylfanyl porphyrazines with bulky phthalimide subtituents in the periphery. Synergic effect with nanostructural components for catalytical properties
    Authors:
    Michal Falkowski, Tomasz Rebis, Lukasz Popenda, Jaroslaw Piskorz, Jacek Dulęba, Joanna Chałupka, Grzegorz Milczarek, Michal P. Marszall
    Conference:
    18th Blue Danube Symposium on Heterocyclic Chemistry (rok: 2019, ), Wydawca: University of Ljubljana, Faculty of Chemistry and Chemical Technology
    Data:
    konferencja 18-21 Wrzesień
    Status:
    Published
  4. Sulfanyl porphyrazines with bulky phthalimide substituents, synthesis, optical and electrochemical properties
    Authors:
    Mina Hassani, Michal Falkowski, Amanda Leda, Tomasz Rebis, Weronika Porolnik, Sandra Gajewska, Natalia Kocot, Michal P. Marszall
    Conference:
    XXVII EFMC International Symposium on Medicinal Chemistry (rok: 2022, ), Wydawca: Société de Chimie Thérapeutique (SCT)
    Data:
    konferencja 4-8 września 2022
    Status:
    Published
  5. Synergiczny efekt porfirazyn siarkowych posiadających peryferyjne ugrupowanie ftamimidowe i nanorurek węglowych w celu poprawy elektrokatalitycznego wykrywania nadtlenku wodoru
    Authors:
    Mina Hassani, Amanda Leda, Michal Falkowski, Weronika Porolnik, Tomasz Rebis, Michal P. Marszall, Grzegorz Milczarek
    Conference:
    BioOrg - IV Ogólnopolskie Sympozjum Chemii Bioorganicznej, Organicznej i Biomateriałów (rok: 2022, ), Wydawca: Wydział Technologii Chemicznej Politechniki Poznańskiej
    Data:
    konferencja 3 grudnia
    Status:
    Published
  6. Synthesis and optical properties of sulfanyl porphyrazines possessing phthalimide substituents in the periphery
    Authors:
    Michal Falkowski, Jaroslaw Piskorz, Ewelina Wieczorek, Adam Sikora, Dominik Mieszkowski, Dariusz T Mlynarczyk, Lukasz Popenda, Jadwiga Mielcarek, Tomasz Goslinski, Michal P. Marszall
    Conference:
    Annual Congress of the Italian Society of Photobiology – SIFB2019 (rok: 2019, ), Wydawca: Italian National Research Council, Bologna Institute of Organic Synthesis & Photoreactivity (ISOF)
    Data:
    konferencja 19-21 Czerwiec
    Status:
    Published