Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Evaluation of neuroprotective properties of piceatannol in model biological systems.

2017/25/N/NZ1/02849

Keywords:

glyceraldehyde-3-phosphate dehydrogenase piceatannol neurodegenerative diseases

Descriptors:

  • NZ1_3: Biophysics
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Joanna Gerszon 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 59 760 PLN

Project start date (Y-m-d): 2018-01-19

Project end date (Y-m-d): 2019-01-18

Project duration:: 12 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase in neurodegenerative processes and the role of low molecular weight compounds in counteracting its aggregation and nuclear translocation
    Authors:
    Joanna Gerszona, Aleksandra Rodacka
    Academic press:
    Ageing Research Reviews (rok: 2018, tom: 48, strony: 21-31), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.arr.2018.09.003 - link to the publication
  2. Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase
    Authors:
    Joanna Gerszon, Eligiusz Serafin, Adam Buczkowski, Sylwia Michlewska, Jakub Antoni Bielnicki, Aleksandra Rodacka
    Academic press:
    PLoS One (rok: 2018, tom: 13, strony: e0190656), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0190656 - link to the publication
  3. Piceatannol effectively counteracts glyceraldehyde-3-phosphate dehydrogenase aggregation and nuclear translocation in hippocampal cells
    Authors:
    Joanna Gerszon, Martyna Wojtala, Sylwia Michlewska, Aleksandra Rodacka
    Academic press:
    Journal of Functional Foods (rok: 2019, tom: 58, strony: 180-188), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jff.2019.05.002 - link to the publication
  1. The role of piceatannol in counteracting GAPDH aggregation and nuclear translocation
    Authors:
    Joanna Gerszon, Aleksandra Rodacka
    Conference:
    20th International Conference on Biochemistry, Biophysics and Molecular Biology (rok: 2018, ), Wydawca: World Academy of Science, Engineering and Technology International Journal of Chemical and Molecular Engineering, World Academy of Science, Engineering and Technology International Journal of Chemical and Molecular Engineering Vol:12, No:4, 2018
    Data:
    konferencja 19-20.04.2018
    Status:
    Published