Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Novel [4+2]-cycloadditions for asymmetric synthesis

2016/23/B/ST5/01927

Keywords:

asymmetric synthesis organocatalysis [4+2]-cycloadditions heterocyclic compounds

Descriptors:

  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Łódzka, Wydział Chemiczny

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Łukasz Albrecht 

Number of co-investigators in the project: 4

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 253 520 PLN

Project start date (Y-m-d): 2017-07-28

Project end date (Y-m-d): 2020-10-27

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Kolumny SFC z chiralnym wypełnieniem (4 szt.) (40 000 PLN)
  2. Piecyk szklany do mikro-destylacji.
  3. Wyparka obrotowa.
  4. Pompa próżniowa.
  5. Chromatograf SFC z fazą mobilną CO2 w stanie nadkrytycznym (SFC) (440 000 PLN)
  6. Zestaw komputerowy z oprogramowaniem (6 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  • Book publications / chapters in book publications (1)
  1. Asymetryczna aminokataliza : użyteczne narzędzie w tworzeniu chemicznej różnorodności
    Authors:
    Skrzyńska Anna, Przydacz Artur, Dyguda Mateusz,Topolska Aleksandra, Albrecht Łukasz
    Academic press:
    Wiadomości chemiczne (rok: 2020, tom: 72, strony: 255-284), Wydawca: Polskie Towarzystwo Chemiczne
    Status:
    Published
    DOI:
    brak - link to the publication
  2. Cyclic 1-Azadienes in the Organocatalytic Inverse-Electron-Demand Aza-Diels-Alder Cycloadditions
    Authors:
    Anna Skrzyńska, Sebastian Frankowski, Łukasz Albrecht
    Academic press:
    Asian Journal of Organic Chemistry (rok: 2020, tom: 9, strony: 1688–1700), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ajoc.202000332 - link to the publication
  3. Intramolecular [2+2]‐cycloaddition in the synthesis of polycyclic tetrahydrothiopyran derivatives bearing a cyclobutane scaffold
    Authors:
    Grzelak, P., Saktura, M., Sieroń, L., Albrecht, Ł.
    Academic press:
    Advanced Synthesis and Catalysis (rok: 2019, tom: 361, strony: 2274-2279), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/adsc.201801739 - link to the publication
  4. The first organocatalytic, ortho-regioselective inverse-electron-demand hetero-Diels–Alder reaction
    Authors:
    Hejmanowska J., Jasiński M., Wojciechowski J., Mlostoń G., Albrecht, Ł.
    Academic press:
    Chemical Communications (rok: 2017, tom: 53, strony: 11472-11475), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C7CC06518C - link to the publication
  5. Aminocatalytic Synthesis of Uracil Derivatives Bearing a Bicyclo[2.2.2]octane Scaffold via a Doubly Cycloadditive Reaction Cascade
    Authors:
    Maciej Saktura, Sebastian Frankowski, Bartłomiej Joachim, Łukasz Albrecht
    Academic press:
    Synthesis (rok: 2021, tom: 53, strony: 309-317), Wydawca: Georg Thieme Verlag KG
    Status:
    Published
    DOI:
    10.1055/s-0040-1707313 - link to the publication
  6. Aromatizative Inverse-Electron-Demand Hetero-Diels-Alder Reaction in the Synthesis of Benzothiophene Derivatives
    Authors:
    Maciej Saktura, Bartłomiej Joachim, Paulina Grzelak, Łukasz Albrecht
    Academic press:
    European Journal of Organic Chemistry (rok: 2019, tom: 2019, strony: 6592–6596), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ejoc.201900884 - link to the publication
  7. Asymmetric Synthesis of [2.2.2]-Bicyclic Lactones via All-Carbon Inverse-Electron-Demand Diels–Alder Reaction
    Authors:
    Maciej Saktura, Paulina Grzelak, Joanna Dybowska, Łukasz Albrecht
    Academic press:
    Organic Letters (rok: 2020, tom: 22, strony: 1813-1817), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.orglett.0c00138 - link to the publication
  8. Deconjugated‐Ketone‐Derived Dienolates in Remote, Stereocontrolled, Aromative aza‐Diels‐Alder Cycloaddition
    Authors:
    Sebastian Frankowski, Anna Skrzyńska, Lesław Sieroń, Łukasz Albrecht
    Academic press:
    Advanced Synthesis and Catalysis (rok: 2020, tom: 362, strony: 2658-2665), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/adsc.202000197 - link to the publication
  1. ISO (THIO)CYANATE-STRATEGY FOR THE ORGANOCATALYTIC SYNTHESISOF SELECTED HETEROCYCLIC STRUCTURES
    Authors:
    Frankowski, S., Więckowska, A., Albrecht, Ł.
    Book:
    TARGETS IN HETEROCYCLIC SYSTEMS (rok: 2018, tom: 22, strony: 298-317), Wydawca: Societa Chimica Italiana
    Status:
    Published

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