Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The PIK3R1 and INPP4B genes - their prognostic and predictive significance and role in ovarian cancer pathogenesis.

2016/23/B/NZ5/00572

Keywords:

PIK3R1 INPP4B prognostic and predictive markers ovarian cancer

Descriptors:

  • NZ5_3:
  • NZ5_5:
  • NZ2_1:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Iwona Krystyna Rzepecka 

Number of co-investigators in the project: 6

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 192 000 PLN

Project start date (Y-m-d): 2017-07-18

Project end date (Y-m-d): 2022-07-17

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. PIK3CA and PIK3R1 mutations in cancer: from the mechanism of activation to PI3K targeted therapies
    Authors:
    Iwona K Rzepecka and Andrzej Tysarowski
    Academic press:
    Oncology in Clinical Practice (rok: 2024, tom: online first, strony: brak), Wydawca: VIA MEDICA
    Status:
    Published
    DOI:
    10.5603/ocp.101216 - link to the publication
  2. High Frequency of PIK3R1 Alterations in Ovarian Cancers: Clinicopathological and Molecular Associations
    Authors:
    Iwona K Rzepecka, Andrzej Tysarowski, Bozena Konopka, Agnieszka Dansonka-Mieszkowska and Jolanta Kupryjanczyk
    Academic press:
    Cancers (rok: 2025, tom: 17 (2), 269, strony: brak), Wydawca: MDPI
    Status:
    Published
  1. INPP4B gene is frequently deregulated via copy number alteration and underexpression in ovarian cancer
    Authors:
    IK Rzepecka, B Konopka, A Podgorska, R Lotocka, EM Cybulska, A Dansonka-Mieszkowska, A Jenike, P Leszczynski, M Lukasik, U Piekarska, A Stachurska, A Tysarowski, J Kupryjanczyk
    Conference:
    22nd European Congress on Gynaecological Oncology (rok: 2021, ), Wydawca: International Journal of Gynecological Cancer
    Data:
    konferencja 23-25.10.2021
    Status:
    Published
  2. EP970 PIK3R1 mRNA expression is associated with copy number alteration in ovarian cancer
    Authors:
    IK Rzepecka, B Konopka, A Podgorska, A Stachurska, R Lotocka, A Budzilowska, A Dansonka-Mieszkowska, P Leszczynski, M Lukasik, U Piekarska, A Tysarowski and J Kupryjanczyk
    Conference:
    21" European Congress on Gynaecological Oncology (rok: 2019, ), Wydawca: International Journal of Gynecological Cancer
    Data:
    konferencja 2-5.11.2019
    Status:
    Published