Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Development of an NK1 receptor homology model based on the data concerning interspecies differences in ligand binding.

2016/23/D/NZ7/03636

Keywords:

NK1 receptor tachykinins substance P homology modelling

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST5_16:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Piotr Lipiński 

Number of co-investigators in the project: 4

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 499 850 PLN

Project start date (Y-m-d): 2017-07-04

Project end date (Y-m-d): 2021-07-03

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. The solid state VCD of a novel N-acylhydrazone trifluoroacetate
    Authors:
    Joanna Rode, Krzysztof Lyczko, Katarzyna Kosińska, Joanna Matalińska, Jolanta Dyniewicz, Aleksandra Misicka, Jan Cz. Dobrowolski, Piotr F.J. Lipiński
    Academic press:
    Specrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Antiproliferative effects of [D-Pro2, D-Trp7,9]-Substance P and aprepitant on several cancer cell lines and their selectivity in comparison to normal cells
    Authors:
    Matalińska, J; Świć, A, Lipiński, P.F.J., Misicka A.
    Academic press:
    Folia Neuropathologica (rok: 2020, tom: 58, strony: 237-244), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/fn.2020.100066 - link to the publication
  3. In Vivo, In Vitro and In Silico Studies of the Hybrid Compound AA3266, an Opioid Agonist/NK1R Antagonist with Selective Cytotoxicity
    Authors:
    Matalińska, J; Lipiński, P.F.J.; Kosson, P.; Kosińska, K.; Misicka, A.
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 20, strony: 7738), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21207738 - link to the publication
  4. Search for N-acylhydrazone-based NK1R ligands with cytotoxic activity
    Authors:
    Katarzyna Kosińska, Joanna Matalińska, Jolanta Dyniewicz, Jolanta Zaborniak, Aleksandra Misicka, Piotr F. J. Lipiński
    Academic press:
    Pharmaceuticals , Wydawca: MDPI
    Status:
    Submitted
    DOI:
    brak - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy