Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Characterization of IL-17-induced VEGF production by human peritoneal mesothelial cells in the context of peritoneal dialysis

2016/23/B/NZ4/03711

Keywords:

IL-17 VEGF peritoneal mesothelium angiogenesis peritonitis peritoneal dialysis

Descriptors:

  • NZ4_4: Pathophysiology
  • NZ5_7: Human disease treatment

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Janusz Witowski 

Number of co-investigators in the project: 3

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 836 400 PLN

Project start date (Y-m-d): 2017-08-24

Project end date (Y-m-d): 2022-06-23

Project duration:: 58 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komora laminarna (30 000 PLN)
  2. Mikroskop odfwrócony (12 000 PLN)
  3. Inubator CO2 (30 000 PLN)
  4. Zestaw do elektroforezy pionowej.

Information in the final report

  • Publication in academic press/journals (3)
  1. IL-17 in peritoneal dialysis-associated inflammation and angiogenesis: conclusions and perspectives.
    Authors:
    Witowski J, Kamhieh-Milz J, Kawka E, Catar R, Jörres A.
    Academic press:
    Frontiers in Physiology (rok: 2018, tom: 9, strony: 1694), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fphys.2018.01694 - link to the publication
  2. Angiogenic role of mesothelium-derived chemokine CXCL1 during unfavorable peritoneal tissue remodeling in patients receiving peritoneal dialysis as renal replacement therapy
    Authors:
    Catar R, Bartosova M, Kawka E, Chen L, Marinovic I, Zhang C, Zhao H, Wu D, Zickler D, Stadnik H, Karczewski M, Kamhieh-Milz J, Jörres A, Moll G, Schmitt CP, Witowski J.
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 13, strony: 821681), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.821681 - link to the publication
  3. Control of neutrophil influx during peritonitis by transcriptional crossregulation of chemokine CXCL1 by IL-17 and IFN-γ
    Authors:
    Catar RA, Chen L, Cuff SM, Kift-Morgan A, Eberl M, Kettritz R, Kamhieh-Milz J, Moll G, Li Q, Zhao H, Kawka E, Zickler D, Parekh G, Davis P, Fraser DJ, Dragun D, Eckardt K-U, Jörres A, Witowski J.
    Academic press:
    J Pathol (rok: 2020, tom: 251, strony: 175-186), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/path.5438 - link to the publication

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