Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Diversity-Oriented Synthesis of alkaloid-like piperidines as novel privileged structures of potential drugs

2016/23/N/ST5/00101

Keywords:

alkaloids piperidine biological activity organic synthesis

Descriptors:

  • ST5_23:
  • ST5_16:
  • ST4_11: Coordination and supramolecular chemistry

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie, Wydział Technologii i Inżynierii Chemicznej

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Tomasz Idzik 

Number of co-investigators in the project: 3

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2017-07-20

Project end date (Y-m-d): 2020-07-19

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Membranowa pompa próżniowa (3 500 PLN)
  2. Wyparka obrotowa (13 900 PLN)
  3. Mieszadło magnetyczne (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Pyridones – Powerful Precursors for the Synthesis of Alkaloids, Their Derivatives, and Alkaloid-Inspired Compounds
    Authors:
    Jacek G. Sośnicki, Tomasz J. Idzik
    Academic press:
    Synthesis (rok: 2019, tom: 51, strony: 3369–3396), Wydawca: Thieme Chemistry
    Status:
    Published
    DOI:
    10.1055/s-0037-1611844 - link to the publication
  2. Synthesis of Polycyclic δ-Lactams with Bridged Benzomorphan Skeleton: Selectivity and Diversity Driven by Substituents
    Authors:
    Jacek G. Sośnicki, Tomasz J. Idzik, Aleksandra Borzyszkowska, Gabriela Maciejewska, Łukasz Struk
    Academic press:
    The Journal of Organic Chemistry (rok: 2018, tom: 83, strony: 1745-1760), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.7b02509 - link to the publication
  3. Magnesiate-Utilized/Benzyne-Mediated Approach to Indenopyridones from 2‑Pyridones: An Attempt To Synthesize the Indenopyridine Core of Haouamine
    Authors:
    Tomasz J. Idzik, Aleksandra Borzyszkowska-Ledwig, Łukasz Struk, Jacek G. Sośnicki
    Academic press:
    Organic Letters (rok: 2019, tom: 21, strony: 9667−9671), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.orglett.9b03806 - link to the publication
  4. Diversity-Oriented Synthesis toward Fused and Bridged Benzobicyclic Piperidin(on)es
    Authors:
    Tomasz J. Idzik, Zofia M. Myk, Jacek G. Sośnicki
    Academic press:
    Journal of Organic Chemistry (rok: 2019, tom: 84, strony: 8046−8066), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.9b00920 - link to the publication