Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Involvement of P2 receptors in pathogenesis of glomerular filtration barrier dysfunction in experimental model of diabetes type 1

2016/23/B/NZ5/02632

Keywords:

diabetes glomerulopathy receptors P2

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Jankowski 

Number of co-investigators in the project: 6

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 788 340 PLN

Project start date (Y-m-d): 2017-07-18

Project end date (Y-m-d): 2021-07-17

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. System do termostabilizacji perfuzatu i środowiska inkubacyjnego.
  2. Laboratoryjna zamrażarka niskotemperaturowa (45 000 PLN)
  3. Mikroskop fluorescencyjny odwrócony z oprogramowaniem umożliwiającym selekcję, detekcję i analizę obrazów fluorescencyjnych (200 000 PLN)
  4. Pompa infuzyjna strzykawkowa dwukierunkowa (16 000 PLN)
  5. Detektor fluorescencyjny do przezskórnego pomiaru GFR z oprogramowaniem (18 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Diabetes Affects the A1 Adenosine Receptor-Dependent Action of Diadenosine Tetraphosphate (Ap4A) on Cortical and Medullary Renal Blood Flow
    Authors:
    Ewelina Kreft, Kornelia Sałaga-Zalesk, Monika Sakowicz-Burkiewicz, Kamil Dąbkowsk, Miroslawa Szczepánska-Konkel , Maciej Jankowski
    Academic press:
    Journal of Vascular Research (rok: 2021, tom: 58, strony: 38–48), Wydawca: Karger AG Basel
    Status:
    Published
    DOI:
    10.1159/000511461 - link to the publication
  2. Suramin enhances the urinary excretion of VEGF‑A in normoglycemic and streptozotocin‑induced diabetic rats
    Authors:
    Gabriela Chyła, Kornelia Sałaga‑Zaleska, Kamil Dąbkowski, Agnieszka Kuchta, Maciej Jankowski
    Academic press:
    Pharmacological Reports (rok: 2021, tom: 73, strony: 841-846), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-021-00236-0 - link to the publication
  3. Effect of suramin on urinary excretion of diabetes-induced glomerular and tubular injury parameters in rats
    Authors:
    Kornelia Sałaga-Zaleska, Piotr Pikul, Ewelina Kreft, Sylwia Herman, Gabriela Chyła, Kamil Dąbkowski, Agnieszka Kuchta, Małgorzata Lenartowicz, Maciej Jankowski
    Academic press:
    Biomedicine & Pharmacotherapy (rok: 2021, tom: 139, strony: 111683), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2021.111683 - link to the publication