Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Mechanisms of global interplay between bacterial stress response, DNA replication and metabolism in Escherichia coli

2016/23/D/NZ1/02601

Keywords:

ppGpp DNA replication metabolism central carbon metabolism

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ1_10: Microbiology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Monika Maciąg-Dorszyńska 

Number of co-investigators in the project: 2

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 678 200 PLN

Project start date (Y-m-d): 2017-07-13

Project end date (Y-m-d): 2023-07-12

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wytrząsarka (20 000 PLN)
  2. Ekran do urządzenia fosfo-imager (40 000 PLN)
  3. Termomikser (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. The Role of Metabolites in the Link between DNA Replication and Central Carbon Metabolism in Escherichia coli
    Authors:
    Klaudyna Krause, Monika Maciag-Dorszynska, Anna Wosinski, Lidia Gaffke, Joanna Morcinek-Orłowska, Estera Rintz, Patrycja Bielanska, Agnieszka Szalewska-Pałasz, Georgi Muskhelishvili, Grzegorz Wegrzyn
    Academic press:
    Gene (rok: 2020, tom: 11(4), strony: 447), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes11040447 - link to the publication
  2. Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis
    Authors:
    Hamid Nouri, Anne-Françoise Monnier, Solveig Fossum-Raunehaug, Monika Maciąg-Dorszyńska, Armelle Cabin-Flaman, François Képès, Grzegorz Węgrzyn, Agnieszka Szalewska-Pałasz, Vic Norris, Kirsten Skarstad, and Laurent Janniere
    Academic press:
    DNA Research (rok: 2018, tom: 25, strony: 641–653), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/dnares/dsy031 - link to the publication
  3. The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates
    Authors:
    Llorenç Fernández-Coll, Monika Maciag-Dorszynska, Krishma Tailor, Stephen Vadia, Petra Anne Levin, Agnieszka Szalewska-Palasz, and Michael Cashel
    Academic press:
    mbio (rok: 2020, tom: 11, strony: e03223-19), Wydawca: ASM
    Status:
    Published
    DOI:
    10.1128/mBio.03223-19 - link to the publication

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