Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Resonance Raman spectroscopy studies of the in vitro and ex vivo haemoglobin adducts with gasotransmitters in biological systems

2016/23/N/ST4/00929

Keywords:

Pophyrins erythrocytes haemoglobin nitric oxide carbon monoxide hydrogen sulfide

Descriptors:

  • ST4_3: Molecular architecture and structure
  • NZ1_2: Biochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Jakub Dybaś 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 99 400 PLN

Project start date (Y-m-d): 2017-07-26

Project end date (Y-m-d): 2020-01-25

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Dysk twardy (325 PLN)
  2. Lactate Scout.
  3. chłodziarka GKv Liebherr 242/X31/19 (3 826 PLN)
  4. CompareVOA (15 689 PLN)
  5. Komputer przenośny (3 500 PLN)
  6. Objektyw do pomiarów imersyjnych (16 000 PLN)
  7. Przyrząd wielofunkcyjny Elmetron CX-601.
  8. Dysk twardy przenośny (300 PLN)
  9. Zużywalne elementy spektrometru (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Book publications / chapters in book publications (1)
  1. Probing Heme Active Sites of Hemoglobin in Functional Red Blood Cells Using Resonance Raman Spectroscopy
    Authors:
    J. Dybas, T. Chiura, K. M. Marzec, P. J. Mak
    Academic press:
    The Journal of Physical Chemistry B (rok: 2021, tom: 125, strony: 3556-3565), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.1c01199 - link to the publication
  2. Raman imaging of haem metabolism in situ in macrophages and Kupffer cells
    Authors:
    J. Dybas, M. Grosicki, M. Baranska, K. M. Marzec
    Academic press:
    Analyst (rok: 2018, tom: 143, strony: 3489-3498), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8AN00282G - link to the publication
  3. Spectroscopy-based characterization of Hb–NO adducts in human red blood cells exposed to NO-donor and endothelium-derived NO
    Authors:
    J. Dybas, P. Berkowicz, B. Proniewski, K. Dziedzic-Kocurek, J. Stanek, M. Baranska, S. Chlopicki, K. M. Marzec
    Academic press:
    Analyst (rok: 2018, tom: 143, strony: 4335-4346), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8AN00302E - link to the publication
  1. 7. Vibrational imaging of proteins: changes in the tissues and cells in the lifestyle disease studies
    Authors:
    K. Majzner, K. Czamara, M. Z. Pacia, J. Dybas, E. Bik, K. Chrabaszcz, E. Wiercigroch, A. Dorosz, A. Wislocka, K. M. Marzec, K. Malek and M. Baranska
    Book:
    Vibrational Spectroscopy in Protein Research (rok: 2020, tom: Rozdział 7, strony: 177-218), Wydawca: Academic Press
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy