Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The impact of TSLP, IL-33 and IL-25 on the interaction between respiratory epithelium, dendritic cells and macrophages in obstructive lung diseases

2016/23/D/NZ5/03279

Keywords:

respiratory epithelium ALI macrophages dendritic cells TSLP IL-33 IL-25 atopy

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Magdalena Paplińska-Goryca 

Number of co-investigators in the project: 6

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 770 800 PLN

Project start date (Y-m-d): 2017-08-11

Project end date (Y-m-d): 2021-08-10

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Woltomierz wraz z wymienną elektrodą.
  2. Cytometr przepływowy (360 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Interactions of nasal epithelium with macrophages and dendritic cells variously alter urban PM-induced inflammation in healthy, asthma and COPD
    Authors:
    Magdalena Paplinska-Goryca, Paulina Misiukiewicz-Stepien, Malgorzata Proboszcz, Patrycja Nejman-Gryz, Katarzyna Gorska, Elwira Zajusz-Zubek, Rafal Krenke
    Academic press:
    Scientific Reports (rok: 2021, tom: 11, strony: 13259), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-021-92626-w - link to the publication
  2. Epithelial-macrophage-dendritic cell interactions impact alarmins expression in asthma and COPD
    Authors:
    Magdalena Paplinska-Goryca, Paulina Misiukiewicz-Stepien, Patrycja Nejman-Gryz, Małgorzata Proboszcz, Michal Mlacki, Katarzyna Gorska, Rafal Krenke
    Academic press:
    Clinical Immunology (rok: 2020, tom: 215, strony: 45308), Wydawca: George C. Tsokos
    Status:
    Published
    DOI:
    10.1016/j.clim.2020.108421 - link to the publication
  3. The Expressions of TSLP, IL-33, and IL-17A in Monocyte Derived Dendritic Cells from Asthma and COPD Patients are Related to Epithelial–Macrophage Interactions
    Authors:
    Paplińska-Goryca Magdalena, Misiukiewicz-Stępień Paulina , Proboszcz Małgorzata , Nejman-Gryz Patrycja, Górska Katarzyna , Krenke Rafał
    Academic press:
    Cells (rok: 2020, tom: 9, strony: 45305), Wydawca: Alexander E. Kalyuzhny
    Status:
    Published
    DOI:
    10.3390/cells9091944 - link to the publication

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