Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The immunoregulatory role of galectin in gastrointestinal nematode infections.

2016/23/B/NZ6/03464

Keywords:

Nematodes immune modulation galectin IgE mast cells Inflammatory bowel disease

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ6_6: Parasitology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Wojskowy Instytut Higieny i Epidemiologii im. gen. Karola Kaczkowskiego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Donskow-Łysoniewska 

Number of co-investigators in the project: 3

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 683 480 PLN

Project start date (Y-m-d): 2017-09-13

Project end date (Y-m-d): 2021-03-12

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  1. Nematode Galectin Binds IgE and Modulates Mast Cell Activity
    Authors:
    Katarzyna Donskow-Łysoniewska, Marta Maruszewska-Cheruiyot, Katarzyna Krawczak- Wójcik, Jorge. F. Gonzalez, Julia. N. Hernández, Michael J. Stear
    Academic press:
    Veterinary Parasitology (rok: 2022, tom: 311, strony: 109807), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.vetpar.2022.109807 - link to the publication
  2. Nematode Galectin Inhibits Basophilic Leukaemia RBL-2H3 Cells Apoptosis in IgE-Mediated Activation
    Authors:
    Marta Maruszewska-Cheruiyot, Ludmiła Szewczak, Katarzyna Krawczak-Wójcik, Michael James Stear and Katarzyna Donskow-Łysoniewska
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25(13), strony: 7419), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms25137419 - link to the publication
  3. Galectins - important players of the immune response to CNS parasitic infection.
    Authors:
    Maruszewska-Cheruiyot M., Stear M.J., Donskow-Łysoniewska K.
    Academic press:
    Brain, Behavior, & Immunity - Health (rok: 2021, ), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbih.2021.100221 - link to the publication
  4. The interaction of host and nematode galectins influences the outcome of gastrointestinal nematode infections.
    Authors:
    Donskow-Łysoniewska K., Maruszewska-Cheruiyot M., Stear M.
    Academic press:
    Parasitology (rok: 2021, tom: 19, strony: 45664), Wydawca: Cambridge University Press
    Status:
    Published
    DOI:
    10.1017/S003118202100007X - link to the publication
  1. Wpływ deplecji leukocytów CD103+ na przebieg EAE u myszy zarażonych nicieniem jelitowym
    Authors:
    K. Krawczak, K. Donskow-Łysoniewska
    Conference:
    IX Ogólnopolska Konferencja "Postępy w Badaniach Biomedycznych (rok: 2018, ), Wydawca: Oficyna Wydawnicza WUM
    Data:
    konferencja 01-02.12.2018
    Status:
    Published
  2. How nematode molecules modulate the immune response.
    Authors:
    Michael Stear, Marta Maruszewska-Cheruiyot & Katarzyna Donskow- Łysoniewska
    Conference:
    VI Zjazd Naukowy Polskiego Towarzystwa Biologii Medycznej (rok: 2024, ), Wydawca: Polskie Towarzystwo Biologii Medycznej
    Data:
    konferencja 19-21.09.2024
    Status:
    Published
  3. Nematode-derived galectin inhibits colitis via modification of mast cells activity.
    Authors:
    Marta Maruszewska Cheruiyot, Katarzyna Krawczak Wójcik, Michael Stear & Katarzyna Donskow Łysoniewska.
    Conference:
    6th European Congress of Immunology. (rok: 2021, ), Wydawca: European Journal of Immunology
    Data:
    konferencja 1-4.09.2021
    Status:
    Published
  4. IMMUNOMODULATORY ROLE OF NEMATODE GALECTIN
    Authors:
    Stear Michael, Krawczak Katarzyna, Donskow-Łysoniewska Katarzyna
    Conference:
    Polish Scientific Networks (rok: 2018, ), Wydawca: PCN
    Data:
    konferencja 21-23.06.2018
    Status:
    Published
  5. Nematode-derived Galectin universal activity – influence of Teladorsagia circumcincta Galectin (Tc-Gal-1) on various species cells
    Authors:
    Marta Maruszewska-Cheruiyot , Maja Machcińska, Katarzyna Krawczak-Wójcik , Ludmiła Szewczak , Magdalena Kierasińska , Michael Stear & Katarzyna Donskow-Łysoniewska
    Conference:
    The 26th Congress of the Polish Parasitological Society (rok: 2022, ), Wydawca: Annals of Parasitology
    Data:
    konferencja 12-15 September 2022
    Status:
    Published

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