Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Phytochemical and biotechnological studies and evaluation of biological activity of magnolia vine species - Schisandra rubriflora

2016/23/D/NZ7/01316

Keywords:

Schisandra rubriflora chemical composition biotechnological studies biological activity in vitro cultures plant drugs

Descriptors:

  • NZ1_9: Biotechnology
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Szopa 

Number of co-investigators in the project: 3

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 311 800 PLN

Project start date (Y-m-d): 2017-08-04

Project end date (Y-m-d): 2022-08-03

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Łaźnia ultradźwiękowa (2 150 PLN)
  2. Lodówko-zamrażarka (1 900 PLN)
  3. Komora z laminarnym poziomym przepływem powietrza (15 800 PLN)
  4. Wytrząsarka do hodowli in vitro (4 450 PLN)
  5. Komputer - laptop (2 800 PLN)

Information in the final report

  • Publication in academic press/journals (10)
  • Book publications / chapters in book publications (3)
  1. Improved production of dibenzocyclooctadiene lignans in the elicited microshoot cultures of Schisandra chinensis (Chinese magnolia vine)
    Authors:
    Szopa A., Kokotkiewicz A., Król A., Luczkiewicz M., Ekiert H.
    Academic press:
    Applied Microbiology and Biotechnology (rok: 2018, tom: 102, strony: 945-959), Wydawca: Springer Berlin Heidelberg
    Status:
    Published
    DOI:
    10.1007/s00253-017-8640-7 - link to the publication
  2. Stimulation of lignan production in Schisandra rubriflora in vitro cultures by elicitation
    Authors:
    Agnieszka Szopa, Michał Dziurka, Paweł Kubica, Karolina Jafernik, Oliwia Siomak, Halina Ekiert
    Academic press:
    Molecules , Wydawca: MDPI
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. Phenolic acid and flavonoid production in agar, agitated and bioreactorgrown microshoot cultures of Schisandra chinensis cv. Sadova No. 1 – a valuable medicinal plant
    Authors:
    Szopa A., Klimek-Szczykutowicz M., Kokotkiewicz A., Dziurka M., Luczkiewicz M., Ekiert H.
    Academic press:
    Journal of Biotechnology (rok: 2019, tom: 305, strony: 61-70), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jbiotec.2019.08.021 - link to the publication
  4. Phytochemical studies and biological activity of three Chinese Schisandra species (Schisandra sphenanthera, Schisandra henryi and Schisandra rubriflora): current findings and future applications
    Authors:
    Szopa A., Barnaś M., Ekiert H.
    Academic press:
    Phytochemistry Reviews (rok: 2019, tom: 18, strony: 109-128), Wydawca: Springer Nature B.V.
    Status:
    Published
    DOI:
    10.1007/s11101-018-9582-0 - link to the publication
  5. Phytochemical studies and biological activity of three Chinese Schisandra species (Schisandra sphenanthera, Schisandra henryi and Schisandra rubriflora): current findings and future applications
    Authors:
    Szopa A., Barnaś M., Ekiert H.
    Academic press:
    Phytochemistry Reviews (rok: 2018, tom: 18, strony: 109–128), Wydawca: Springer Netherlands
    Status:
    Published
    DOI:
    10.1007/s11101-018-9582-0 - link to the publication
  6. Schisandra rubriflora Fruit and Leaves as Promising New Materials of High Biological Potential: Lignan Profiling and Effect-Directed Analysis
    Authors:
    Ewelina Sobstyl; Agnieszka Szopa; Michał Dziurka; Halina Ekiert; Hanna Nikolaichuk; Irena Maria Choma
    Academic press:
    Molecules (rok: 2022, tom: 27, strony: 2116), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules27072116 - link to the publication
  7. Schisandra rubriflora Plant Material and In Vitro Microshoot Cultures as Rich Sources of Natural Phenolic Antioxidants
    Authors:
    Szopa A., Dziurka M., Granica S., Klimek-Szczykutowicz M., Kubica P., Warzecha A., Jafernik K., Ekiert H.
    Academic press:
    Antioxidants (rok: 2020, tom: 9 (6), strony: 488), Wydawca: MDPI - MDPI - Molecular Diversity Preservation International and Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/antiox9060488 - link to the publication
  8. Targeted lignan profiling and anti-inflammatory properties of Schisandra rubriflora and Schisandra chinensis extracts
    Authors:
    Szopa A., Dziurka M., Warzecha A., Kubica P., Klimek-Szczykutowicz M., Ekiert H.
    Academic press:
    Molecules (rok: 2018, tom: 23, strony: 1-16, E3103), Wydawca: MDPI - Molecular Diversity Preservation International and Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/molecules23123103 - link to the publication
  9. Bioreactor type affects the accumulation of phenolic acids and flavonoids in microshoot cultures of Schisandra chinensis (Turcz.) Baill.
    Authors:
    Szopa A., Kokotkiewicz A., Bednarz M., Jafernik K., Luczkiewicz M., Ekiert H.
    Academic press:
    Plant Cell Tissue and Organ Culture (rok: 2019, tom: 139, strony: 199-206), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11240-019-01676-6 - link to the publication
  10. Phytochemical and biotechnological studies on Schisandra chinensis cultivar Sadova No. 1 – a high utility medicinal plant
    Authors:
    Szopa A., Klimek-Szczykutowicz M., Kokotkiewicz A., Maślanka A., Król A., Łuczkiewicz M., Ekiert H.
    Academic press:
    Applied Microbiology and Biotechnology (rok: 2018, tom: 102, strony: 5105-5120), Wydawca: Springer Berlin Heidelberg
    Status:
    Published
    DOI:
    10.1007/s00253-018-8981-x - link to the publication
  1. Cultures of Medicinal Plants In Vitro as a Potential Rich Source of Antioxidants.
    Authors:
    Ekiert H., Kubica P., Kwiecień I., Jafernik K., Klimek-Szczykutowicz M., Szopa A.
    Book:
    Plant Antioxidants and Health. Reference Series in Phytochemistry (rok: 2021, tom: 1, strony: 16072), Wydawca: Springer, Cham.
    Status:
    Published
  2. Different Types of In Vitro Cultures of Schisandra chinensis and Its Cultivar (S. chinensis cv. Sadova): A Rich Potential Source of Specific Lignans and Phenolic Compounds
    Authors:
    Szopa A., Kokotkiewicz A., Klimek-Szczykutowicz M., Luczkiewicz M., Ekiert H.
    Book:
    Plant Cell and Tissue Differentiation and Secondary Metabolites. Reference Series in Phytochemistry. (rok: 2020, tom: 1, strony: 45318), Wydawca: Springer Nature Switzerland
    Status:
    Published
  3. Schisandra chinensis and Schisandra sphenanthera—From Traditional Far Eastern Medicine to International Utilization
    Authors:
    Karolina Jafernik, Halina Ekiert, Agnieszka Szopa
    Book:
    Medicinal Plants. Sustainable Development and Biodiversity (rok: 2021, tom: 28, strony: 179-227), Wydawca: Springer, Cham.
    Status:
    Published

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